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Implementation of QbD Approach to the Development of Chromatographic Methods for the Determination of Complete Impurity Profile of Substance on the Preclinical and Clinical Step of Drug Discovery Studies.
Gurba-Bryśkiewicz L, Dawid U, Smuga DA, Maruszak W, Delis M, Szymczak K, Stypik B, Moroz A, Błocka A, Mroczkiewicz M, Dubiel K, Wieczorek M. Gurba-Bryśkiewicz L, et al. Among authors: stypik b. Int J Mol Sci. 2022 Sep 14;23(18):10720. doi: 10.3390/ijms231810720. Int J Mol Sci. 2022. PMID: 36142622 Free PMC article.
A novel JAK/ROCK inhibitor, CPL409116, demonstrates potent efficacy in the mouse model of systemic lupus erythematosus.
Dulak-Lis M, Bujak A, Gala K, Banach M, Kędzierska U, Miszkiel J, Hucz-Kalitowska J, Mroczkiewicz M, Stypik B, Szymczak K, Gunerka P, Dubiel K, Zygmunt BM, Wieczorek M, Pieczykolan JS. Dulak-Lis M, et al. Among authors: stypik b. J Pharmacol Sci. 2021 Apr;145(4):340-348. doi: 10.1016/j.jphs.2021.02.002. Epub 2021 Feb 9. J Pharmacol Sci. 2021. PMID: 33712286 Free article.