Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

1,236 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2.
Welker A, Kersten C, Müller C, Madhugiri R, Zimmer C, Müller P, Zimmermann R, Hammerschmidt S, Maus H, Ziebuhr J, Sotriffer C, Schirmeister T. Welker A, et al. Among authors: zimmer c. ChemMedChem. 2021 Jan 19;16(2):340-354. doi: 10.1002/cmdc.202000548. Epub 2020 Oct 16. ChemMedChem. 2021. PMID: 32930481 Free PMC article.
Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies.
Jung S, Fuchs N, Johe P, Wagner A, Diehl E, Yuliani T, Zimmer C, Barthels F, Zimmermann RA, Klein P, Waigel W, Meyr J, Opatz T, Tenzer S, Distler U, Räder HJ, Kersten C, Engels B, Hellmich UA, Klein J, Schirmeister T. Jung S, et al. Among authors: zimmer c. J Med Chem. 2021 Aug 26;64(16):12322-12358. doi: 10.1021/acs.jmedchem.1c01002. Epub 2021 Aug 11. J Med Chem. 2021. PMID: 34378914
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.
Previti S, Ettari R, Calcaterra E, Di Chio C, Ravichandran R, Zimmer C, Hammerschmidt S, Wagner A, Bogacz M, Cosconati S, Schirmeister T, Zappalà M. Previti S, et al. Among authors: zimmer c. ACS Med Chem Lett. 2022 Jun 30;13(7):1083-1090. doi: 10.1021/acsmedchemlett.2c00084. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859868 Free PMC article.
A structure-based virtual high-throughput screening, molecular docking, molecular dynamics and MM/PBSA study identified novel putative drug-like dual inhibitors of trypanosomal cruzain and rhodesain cysteine proteases.
Eurtivong C, Zimmer C, Schirmeister T, Butkinaree C, Saruengkhanphasit R, Niwetmarin W, Ruchirawat S, Bhambra AS. Eurtivong C, et al. Among authors: zimmer c. Mol Divers. 2024 Apr;28(2):531-551. doi: 10.1007/s11030-023-10600-2. Epub 2023 Jan 8. Mol Divers. 2024. PMID: 36617352
Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study.
Müller P, Meta M, Meidner JL, Schwickert M, Meyr J, Schwickert K, Kersten C, Zimmer C, Hammerschmidt SJ, Frey A, Lahu A, de la Hoz-Rodríguez S, Agost-Beltrán L, Rodríguez S, Diemer K, Neumann W, Gonzàlez FV, Engels B, Schirmeister T. Müller P, et al. Among authors: zimmer c. Int J Mol Sci. 2023 Apr 13;24(8):7226. doi: 10.3390/ijms24087226. Int J Mol Sci. 2023. PMID: 37108388 Free PMC article.
Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis.
Previti S, Ettari R, Di Chio C, Legac J, Bogacz M, Zimmer C, Schirmeister T, Rosenthal PJ, Zappalà M. Previti S, et al. Among authors: zimmer c. Bioorg Chem. 2023 Aug;137:106587. doi: 10.1016/j.bioorg.2023.106587. Epub 2023 May 4. Bioorg Chem. 2023. PMID: 37163812 Free article.
1,236 results