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Dolaflexin: A Novel Antibody-Drug Conjugate Platform Featuring High Drug Loading and a Controlled Bystander Effect.
Yurkovetskiy AV, Bodyak ND, Yin M, Thomas JD, Clardy SM, Conlon PR, Stevenson CA, Uttard A, Qin L, Gumerov DR, Ter-Ovanesyan E, Bu C, Johnson AJ, Gurijala VR, McGillicuddy D, DeVit MJ, Poling LL, Protopopova M, Xu L, Zhang Q, Park PU, Bergstrom DA, Lowinger TB. Yurkovetskiy AV, et al. Among authors: thomas jd. Mol Cancer Ther. 2021 May;20(5):885-895. doi: 10.1158/1535-7163.MCT-20-0166. Epub 2021 Mar 15. Mol Cancer Ther. 2021. PMID: 33722857
Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates.
Duvall JR, Thomas JD, Bukhalid RA, Catcott KC, Bentley KW, Collins SD, Eitas T, Jones BD, Kelleher EW, Lancaster K, Protopopova M, Ray SS, Ter-Ovanesyan E, Xu L, Yang L, Zurita J, Damelin M, Toader D, Lowinger TB. Duvall JR, et al. Among authors: thomas jd. J Med Chem. 2023 Aug 10;66(15):10715-10733. doi: 10.1021/acs.jmedchem.3c00907. Epub 2023 Jul 24. J Med Chem. 2023. PMID: 37486969 Free PMC article.
Development of a Novel DNA Mono-alkylator Platform for Antibody-Drug Conjugates.
Thomas JD, Yurkovetskiy AV, Yin M, Bodyak ND, Tang S, Protopopova M, Kelleher E, Jones B, Yang L, Custar D, Catcott KC, Demady DR, Collins SD, Xu L, Bu C, Qin L, Ter-Ovanesyan E, Damelin M, Toader D, Lowinger TB. Thomas JD, et al. Mol Cancer Ther. 2024 Apr 2;23(4):541-551. doi: 10.1158/1535-7163.MCT-23-0622. Mol Cancer Ther. 2024. PMID: 38354416
Lessons for a learning health system: Effectively communicating to patients about research with their health information and biospecimens.
Spector-Bagdady K, Ryan KA, Chen L, Giacobone C, Jagsi R, Hamasha R, Hendy K, Thomas JD, Milne JM, Vinson AH, Platt J. Spector-Bagdady K, et al. Among authors: thomas jd. Learn Health Syst. 2024 Sep 13;9(1):e10450. doi: 10.1002/lrh2.10450. eCollection 2025 Jan. Learn Health Syst. 2024. PMID: 39822922 Free PMC article.
Defining Echocardiographic Degrees of Right Heart Size and Function in Pulmonary Vascular Disease from the PVDOMICS Study.
Mukherjee M, Mathai SC, Jellis C, Freed BH, Yanek LR, Agoglia H, Chiu C, Jani VP, Simpson CE, Brittain EL, Tang WHW, Park MM, Hemnes AR, Rosenzweig EB, Rischard FP, Frantz RP, Hassoun PM, Beck G, Hill NS, Erzurum S, Thomas JD, Kwon D, Leopold JA, Horn EM, Kim J; PVDOMICS Study Group. Mukherjee M, et al. Among authors: thomas jd. Circ Cardiovasc Imaging. 2024 Oct;17(10):e017074. doi: 10.1161/circimaging.124.017074. Epub 2024 Oct 15. Circ Cardiovasc Imaging. 2024. PMID: 39691460
1,143 results