Staals RHJ - Search Results

1

Structure of a type IV CRISPR-Cas ribonucleoprotein complex.

Zhou Y, Bravo JPK, Taylor HN, Steens JA, Jackson RN, Staals RHJ, Taylor DW. Zhou Y, et al. Among authors: staals rhj. iScience. 2021 Feb 17;24(3):102201. doi: 10.1016/j.isci.2021.102201. eCollection 2021 Mar 19. iScience. 2021. PMID: 33733066 Free PMC article.

2

Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus.

Staals RHJ, Agari Y, Maki-Yonekura S, Zhu Y, Taylor DW, van Duijn E, Barendregt A, Vlot M, Koehorst JJ, Sakamoto K, Masuda A, Dohmae N, Schaap PJ, Doudna JA, Heck AJR, Yonekura K, van der Oost J, Shinkai A. Staals RHJ, et al. Mol Cell. 2013 Oct 10;52(1):135-145. doi: 10.1016/j.molcel.2013.09.013. Mol Cell. 2013. PMID: 24119403 Free PMC article.

3

RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus.

Staals RH, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, Barendregt A, Koehorst JJ, Vlot M, Neupane N, Varossieau K, Sakamoto K, Suzuki T, Dohmae N, Yokoyama S, Schaap PJ, Urlaub H, Heck AJ, Nogales E, Doudna JA, Shinkai A, van der Oost J. Staals RH, et al. Mol Cell. 2014 Nov 20;56(4):518-30. doi: 10.1016/j.molcel.2014.10.005. Epub 2014 Nov 6. Mol Cell. 2014. PMID: 25457165 Free PMC article.

4

Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning.

Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA. Taylor DW, et al. Science. 2015 May 1;348(6234):581-5. doi: 10.1126/science.aaa4535. Epub 2015 Apr 2. Science. 2015. PMID: 25837515 Free PMC article.

5

Coevolution between bacterial CRISPR-Cas systems and their bacteriophages.

Watson BNJ, Steens JA, Staals RHJ, Westra ER, van Houte S. Watson BNJ, et al. Among authors: staals rhj. Cell Host Microbe. 2021 May 12;29(5):715-725. doi: 10.1016/j.chom.2021.03.018. Cell Host Microbe. 2021. PMID: 33984274 Free article. Review.

6

SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation.

Steens JA, Zhu Y, Taylor DW, Bravo JPK, Prinsen SHP, Schoen CD, Keijser BJF, Ossendrijver M, Hofstra LM, Brouns SJJ, Shinkai A, van der Oost J, Staals RHJ. Steens JA, et al. Among authors: staals rhj. Nat Commun. 2021 Aug 19;12(1):5033. doi: 10.1038/s41467-021-25337-5. Nat Commun. 2021. PMID: 34413302 Free PMC article.

7

The diverse arsenal of type III CRISPR-Cas-associated CARF and SAVED effectors.

Steens JA, Salazar CRP, Staals RHJ. Steens JA, et al. Among authors: staals rhj. Biochem Soc Trans. 2022 Oct 31;50(5):1353-1364. doi: 10.1042/BST20220289. Biochem Soc Trans. 2022. PMID: 36282000 Free PMC article. Review.

8

Compact but mighty: Biology and applications of type III-E CRISPR-Cas systems.

Steens JA, van der Oost J, Staals RHJ. Steens JA, et al. Among authors: staals rhj. Mol Cell. 2022 Dec 1;82(23):4405-4406. doi: 10.1016/j.molcel.2022.11.007. Mol Cell. 2022. PMID: 36459983 Free article.

9

Type III-B CRISPR-Cas cascade of proteolytic cleavages.

Steens JA, Bravo JPK, Salazar CRP, Yildiz C, Amieiro AM, Köstlbacher S, Prinsen SHP, Andres AS, Patinios C, Bardis A, Barendregt A, Scheltema RA, Ettema TJG, van der Oost J, Taylor DW, Staals RHJ. Steens JA, et al. Among authors: staals rhj. Science. 2024 Feb 2;383(6682):512-519. doi: 10.1126/science.adk0378. Epub 2024 Feb 1. Science. 2024. PMID: 38301007

10

CRISPR-Cas systems preferentially target the leading regions of MOBF conjugative plasmids.

Westra ER, Staals RH, Gort G, Høgh S, Neumann S, de la Cruz F, Fineran PC, Brouns SJ. Westra ER, et al. RNA Biol. 2013 May;10(5):749-61. doi: 10.4161/rna.24202. Epub 2013 Mar 27. RNA Biol. 2013. PMID: 23535265 Free PMC article.

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