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Population exposure-efficacy and exposure-safety analyses for rucaparib in patients with recurrent ovarian carcinoma from Study 10 and ARIEL2.
Konecny GE, Oza AM, Tinker AV, Oaknin A, Shapira-Frommer R, Ray-Coquard I, Aghajanian C, Coleman RL, O'Malley DM, Leary A, Chen LM, Provencher D, Ma L, Brenton JD, Castro C, Green M, Simmons AD, Beltman J, Harding T, Lin KK, Goble S, Maloney L, Kristeleit RS, McNeish IA, Swisher EM, Xiao JJ. Konecny GE, et al. Among authors: beltman j. Gynecol Oncol. 2021 Jun;161(3):668-675. doi: 10.1016/j.ygyno.2021.03.015. Epub 2021 Mar 19. Gynecol Oncol. 2021. PMID: 33752918 Free PMC article.
Clinical Pharmacokinetics and Pharmacodynamics of Rucaparib.
Liao M, Beltman J, Giordano H, Harding TC, Maloney L, Simmons AD, Xiao JJ. Liao M, et al. Among authors: beltman j. Clin Pharmacokinet. 2022 Nov;61(11):1477-1493. doi: 10.1007/s40262-022-01157-8. Epub 2022 Sep 15. Clin Pharmacokinet. 2022. PMID: 36107395 Free PMC article. Review.
Evaluation of Drug-Drug Interactions of Rucaparib and CYP1A2, CYP2C9, CYP2C19, CYP3A, and P-gp Substrates in Patients With an Advanced Solid Tumor.
Xiao JJ, Nowak D, Ramlau R, Tomaszewska-Kiecana M, Wysocki PJ, Isaacson J, Beltman J, Nash E, Kaczanowski R, Arold G, Watkins S. Xiao JJ, et al. Among authors: beltman j. Clin Transl Sci. 2019 Jan;12(1):58-65. doi: 10.1111/cts.12600. Epub 2018 Dec 20. Clin Transl Sci. 2019. PMID: 30427584 Free PMC article. Clinical Trial.
Pharmacokinetics and safety of rucaparib in patients with advanced solid tumors and hepatic impairment.
Grechko N, Skarbova V, Tomaszewska-Kiecana M, Ramlau R, Centkowski P, Drew Y, Dziadziuszko R, Zemanova M, Beltman J, Nash E, Habeck J, Liao M, Xiao J. Grechko N, et al. Among authors: beltman j. Cancer Chemother Pharmacol. 2021 Aug;88(2):259-270. doi: 10.1007/s00280-021-04278-2. Epub 2021 Apr 28. Cancer Chemother Pharmacol. 2021. PMID: 33909097 Free PMC article. Clinical Trial.
Evaluation of absorption, distribution, metabolism, and excretion of [14C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors.
Liao M, Watkins S, Nash E, Isaacson J, Etter J, Beltman J, Fan R, Shen L, Mutlib A, Kemeny V, Pápai Z, van Tilburg P, Xiao JJ. Liao M, et al. Among authors: beltman j. Invest New Drugs. 2020 Jun;38(3):765-775. doi: 10.1007/s10637-019-00815-2. Epub 2019 Jun 27. Invest New Drugs. 2020. PMID: 31250355 Free PMC article. Clinical Trial.
Outcomes of endometrial cancer prevention strategies in patients with Lynch syndrome: a nationwide cohort study in the Netherlands.
Eikenboom EL, van Leeuwen L, Groenendijk F, Woolderink JM, Van Altena AM, Van Leerdam ME, Spaander MCW, van Doorn HC, Wagner A; collaborative investigators from the Dutch Foundation for Detection of Hereditary Tumors. Eikenboom EL, et al. EClinicalMedicine. 2024 Dec 21;79:103006. doi: 10.1016/j.eclinm.2024.103006. eCollection 2025 Jan. EClinicalMedicine. 2024. PMID: 39816931 Free PMC article.
Development and validation of artificial intelligence models for early detection of postoperative infections (PERISCOPE): a multicentre study using electronic health record data.
van der Meijden SL, van Boekel AM, Schinkelshoek LJ, van Goor H, Steyerberg EW, Nelissen RGHH, Mesotten D, Geerts BF, de Boer MGJ, Arbous MS; PERISCOPE Group. van der Meijden SL, et al. Lancet Reg Health Eur. 2024 Dec 5;49:101163. doi: 10.1016/j.lanepe.2024.101163. eCollection 2025 Feb. Lancet Reg Health Eur. 2024. PMID: 39720095 Free PMC article.
124 results