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Page 1
The evolutionary history of ACE2 usage within the coronavirus subgenus Sarbecovirus.
Wells HL, Letko M, Lasso G, Ssebide B, Nziza J, Byarugaba DK, Navarrete-Macias I, Liang E, Cranfield M, Han BA, Tingley MW, Diuk-Wasser M, Goldstein T, Johnson CK, Mazet JAK, Chandran K, Munster VJ, Gilardi K, Anthony SJ. Wells HL, et al. Among authors: chandran k. Virus Evol. 2021 Feb 5;7(1):veab007. doi: 10.1093/ve/veab007. eCollection 2021 Jan. Virus Evol. 2021. PMID: 33754082 Free PMC article.
The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses.
Goldstein T, Anthony SJ, Gbakima A, Bird BH, Bangura J, Tremeau-Bravard A, Belaganahalli MN, Wells HL, Dhanota JK, Liang E, Grodus M, Jangra RK, DeJesus VA, Lasso G, Smith BR, Jambai A, Kamara BO, Kamara S, Bangura W, Monagin C, Shapira S, Johnson CK, Saylors K, Rubin EM, Chandran K, Lipkin WI, Mazet JAK. Goldstein T, et al. Among authors: chandran k. Nat Microbiol. 2018 Oct;3(10):1084-1089. doi: 10.1038/s41564-018-0227-2. Epub 2018 Aug 27. Nat Microbiol. 2018. PMID: 30150734 Free PMC article.
Author Correction: The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses.
Goldstein T, Anthony SJ, Gbakima A, Bird BH, Bangura J, Tremeau-Bravard A, Belaganahalli MN, Wells HL, Dhanota JK, Liang E, Grodus M, Jangra RK, DeJesus VA, Lasso G, Smith BR, Jambai A, Kamara BO, Kamara S, Bangura W, Monagin C, Shapira S, Johnson CK, Saylors K, Rubin EM, Chandran K, Lipkin WI, Mazet JAK. Goldstein T, et al. Among authors: chandran k. Nat Microbiol. 2018 Dec;3(12):1486. doi: 10.1038/s41564-018-0315-3. Nat Microbiol. 2018. PMID: 30410089 Free PMC article.
Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection.
Wec AZ, Bornholdt ZA, He S, Herbert AS, Goodwin E, Wirchnianski AS, Gunn BM, Zhang Z, Zhu W, Liu G, Abelson DM, Moyer CL, Jangra RK, James RM, Bakken RR, Bohorova N, Bohorov O, Kim DH, Pauly MH, Velasco J, Bortz RH 3rd, Whaley KJ, Goldstein T, Anthony SJ, Alter G, Walker LM, Dye JM, Zeitlin L, Qiu X, Chandran K. Wec AZ, et al. Among authors: chandran k. Cell Host Microbe. 2019 Jan 9;25(1):39-48.e5. doi: 10.1016/j.chom.2018.12.004. Cell Host Microbe. 2019. PMID: 30629917 Free PMC article.
The evolutionary history of ACE2 usage within the coronavirus subgenus Sarbecovirus.
Wells HL, Letko M, Lasso G, Ssebide B, Nziza J, Byarugaba DK, Navarrete-Macias I, Liang E, Cranfield M, Han BA, Tingley MW, Diuk-Wasser M, Goldstein T, Johnson CK, Mazet J, Chandran K, Munster VJ, Gilardi K, Anthony SJ. Wells HL, et al. Among authors: chandran k. bioRxiv [Preprint]. 2021 Jan 22:2020.07.07.190546. doi: 10.1101/2020.07.07.190546. bioRxiv. 2021. Update in: Virus Evol. 2021 Feb 05;7(1):veab007. doi: 10.1093/ve/veab007 PMID: 32676605 Free PMC article. Updated. Preprint.
2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.
Kuhn JH, Adkins S, Alioto D, Alkhovsky SV, Amarasinghe GK, Anthony SJ, Avšič-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Bartonička T, Basler C, Bavari S, Beer M, Bente DA, Bergeron É, Bird BH, Blair C, Blasdell KR, Bradfute SB, Breyta R, Briese T, Brown PA, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Buzkan N, Calisher CH, Cao M, Casas I, Chamberlain J, Chandran K, Charrel RN, Chen B, Chiumenti M, Choi IR, Clegg JCS, Crozier I, da Graça JV, Dal Bó E, Dávila AMR, de la Torre JC, de Lamballerie X, de Swart RL, Di Bello PL, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolja VV, Dolnik O, Drebot MA, Drexler JF, Dürrwald R, Dufkova L, Dundon WG, Duprex WP, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K, Fernandes J, Fooks AR, Formenty PBH, Forth LF, Fouchier RAM, Freitas-Astúa J, Gago-Zachert S, Gāo GF, García ML, García-Sastre A, Garrison AR, Gbakima A, Goldstein T, Gonzalez JJ, Griffiths A, Groschup MH, Günther S, Guterres A, Hall RA, Hammond J, Hassan M, Hepojoki J, Hepojoki S, Hetzel U, Hewson R, Hoffmann B, Hongo S, Höper D, Horie M, Hughes HR, Hyndman TH, Jambai A, Jardim R, Jiāng D, Jin Q, Jonson GB, Junglen S, Karadağ S, Keller KE, Klempa … See abstract for full author list ➔ Kuhn JH, et al. Among authors: chandran k. Arch Virol. 2020 Dec;165(12):3023-3072. doi: 10.1007/s00705-020-04731-2. Epub 2020 Sep 4. Arch Virol. 2020. PMID: 32888050 Free PMC article.
Distinct pathways for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses.
Tse AL, Acreman CM, Ricardo-Lax I, Berrigan J, Lasso G, Balogun T, Kearns FL, Casalino L, McClain GL, Chandran AM, Lemeunier C, Amaro RE, Rice CM, Jangra RK, McLellan JS, Chandran K, Miller EH. Tse AL, et al. Among authors: chandran k. PLoS Pathog. 2024 Nov 15;20(11):e1012704. doi: 10.1371/journal.ppat.1012704. eCollection 2024 Nov. PLoS Pathog. 2024. PMID: 39546542 Free PMC article.
Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning.
Lasso G, Grodus M, Valencia E, DeJesus V, Liang E, Delwel I, Bortz RH 3rd, Lupyan D, Ehrlich HY, Castellanos AA, Gazzo A, Wells HL, Wacharapluesadee S, Tremeau-Bravard A, Seetahal JFR, Hughes T, Lee J, Lee MH, Sjodin AR, Geldenhuys M, Mortlock M, Navarrete-Macias I, Gilardi K, Willig MR, Nava AFD, Loh EH, Asrat M, Smiley-Evans T, Magesa WS, Zikankuba S, Wolking D, Suzán G, Ojeda-Flores R, Carrington CVF, Islam A, Epstein JH, Markotter W, Johnson CK, Goldstein T, Han BA, Mazet JAK, Jangra RK, Chandran K, Anthony SJ. Lasso G, et al. Among authors: chandran k. Cell Host Microbe. 2025 Jan 15:S1931-3128(24)00483-9. doi: 10.1016/j.chom.2024.12.016. Online ahead of print. Cell Host Microbe. 2025. PMID: 39818205
Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein.
Wec AZ, Wrapp D, Herbert AS, Maurer D, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, Champney E, Burnina I, Brown M, Lin S, Sinclair M, Johnson C, Pudi S, Bortz R 3rd, Wirchnianski AS, Laudermilch E, Florez C, Fels JM, O'Brien CM, Graham BS, Nemazee D, Burton DR, Baric RS, Voss JE, Chandran K, Dye JM, McLellan JS, Walker LM. Wec AZ, et al. Among authors: chandran k. bioRxiv [Preprint]. 2020 May 16:2020.05.15.096511. doi: 10.1101/2020.05.15.096511. bioRxiv. 2020. PMID: 32511337 Free PMC article. Preprint.
537 results