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Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations.
Pei J, Schuldt M, Nagyova E, Gu Z, El Bouhaddani S, Yiangou L, Jansen M, Calis JJA, Dorsch LM, Blok CS, van den Dungen NAM, Lansu N, Boukens BJ, Efimov IR, Michels M, Verhaar MC, de Weger R, Vink A, van Steenbeek FG, Baas AF, Davis RP, Uh HW, Kuster DWD, Cheng C, Mokry M, van der Velden J, Asselbergs FW, Harakalova M. Pei J, et al. Among authors: gu z. Clin Epigenetics. 2021 Mar 23;13(1):61. doi: 10.1186/s13148-021-01043-3. Clin Epigenetics. 2021. PMID: 33757590 Free PMC article.
Statistical integration of two omics datasets using GO2PLS.
Gu Z, El Bouhaddani S, Pei J, Houwing-Duistermaat J, Uh HW. Gu Z, et al. BMC Bioinformatics. 2021 Mar 18;22(1):131. doi: 10.1186/s12859-021-03958-3. BMC Bioinformatics. 2021. PMID: 33736604 Free PMC article.
Artificial intelligence to enhance clinical value across the spectrum of cardiovascular healthcare.
Gill SK, Karwath A, Uh HW, Cardoso VR, Gu Z, Barsky A, Slater L, Acharjee A, Duan J, Dall'Olio L, El Bouhaddani S, Chernbumroong S, Stanbury M, Haynes S, Asselbergs FW, Grobbee DE, Eijkemans MJC, Gkoutos GV, Kotecha D; BigData@Heart Consortium and the cardAIc group. Gill SK, et al. Among authors: gu z. Eur Heart J. 2023 Mar 1;44(9):713-725. doi: 10.1093/eurheartj/ehac758. Eur Heart J. 2023. PMID: 36629285 Free PMC article.
TP53 Mutations are Associated with CD19 Negative Relapse and Inferior Outcomes after Blinatumomab in Adults with ALL.
Aldoss I, Li S, Zhang J, Clark MC, Agrawal V, Pourhassan H, Koller PB, Aribi A, Ali H, Blackmon A, Otoukesh S, Sandhu KS, Ball BJ, Arslan S, Artz AS, Amanam I, Al Malki MM, Salhotra A, Kovacsovics TJ, Murphy LA, Afkhami M, Ngo D, Tinajero J, Gu Z, Becker PS, Nakamura R, Stein AS, Marcucci G, Forman SJ, Pullarkat VA. Aldoss I, et al. Among authors: gu z. Blood Adv. 2025 Jan 16:bloodadvances.2024014986. doi: 10.1182/bloodadvances.2024014986. Online ahead of print. Blood Adv. 2025. PMID: 39820649
7,113 results