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Page 1
Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies.
Greaney AJ, Starr TN, Barnes CO, Weisblum Y, Schmidt F, Caskey M, Gaebler C, Cho A, Agudelo M, Finkin S, Wang Z, Poston D, Muecksch F, Hatziioannou T, Bieniasz PD, Robbiani DF, Nussenzweig MC, Bjorkman PJ, Bloom JD. Greaney AJ, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Mar 18:2021.03.17.435863. doi: 10.1101/2021.03.17.435863. bioRxiv. 2021. Update in: Nat Commun. 2021 Jul 7;12(1):4196. doi: 10.1038/s41467-021-24435-8 PMID: 33758856 Free PMC article. Updated. Preprint.
Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies.
Muecksch F, Weisblum Y, Barnes CO, Schmidt F, Schaefer-Babajew D, Lorenzi JCC, Flyak AI, DeLaitsch AT, Huey-Tubman KE, Hou S, Schiffer CA, Gaebler C, Wang Z, Da Silva J, Poston D, Finkin S, Cho A, Cipolla M, Oliveira TY, Millard KG, Ramos V, Gazumyan A, Rutkowska M, Caskey M, Nussenzweig MC, Bjorkman PJ, Hatziioannou T, Bieniasz PD. Muecksch F, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Mar 8:2021.03.07.434227. doi: 10.1101/2021.03.07.434227. bioRxiv. 2021. Update in: Immunity. 2021 Aug 10;54(8):1853-1868.e7. doi: 10.1016/j.immuni.2021.07.008 PMID: 33758864 Free PMC article. Updated. Preprint.
Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York.
West AP Jr, Wertheim JO, Wang JC, Vasylyeva TI, Havens JL, Chowdhury MA, Gonzalez E, Fang CE, Di Lonardo SS, Hughes S, Rakeman JL, Lee HH, Barnes CO, Gnanapragasam PNP, Yang Z, Gaebler C, Caskey M, Nussenzweig MC, Keeffe JR, Bjorkman PJ. West AP Jr, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Apr 22:2021.02.14.431043. doi: 10.1101/2021.02.14.431043. bioRxiv. 2021. Update in: Nat Commun. 2021 Aug 9;12(1):4886. doi: 10.1038/s41467-021-25168-4 PMID: 33907745 Free PMC article. Updated. Preprint.
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Jette CA, Cohen AA, Gnanapragasam PNP, Muecksch F, Lee YE, Huey-Tubman KE, Schmidt F, Hatziioannou T, Bieniasz PD, Nussenzweig MC, West AP Jr, Keeffe JR, Bjorkman PJ, Barnes CO. Jette CA, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Apr 26:2021.04.23.441195. doi: 10.1101/2021.04.23.441195. bioRxiv. 2021. Update in: Cell Rep. 2021 Sep 28;36(13):109760. doi: 10.1016/j.celrep.2021.109760 PMID: 33948592 Free PMC article. Updated. Preprint.
Naturally enhanced neutralizing breadth to SARS-CoV-2 after one year.
Wang Z, Muecksch F, Schaefer-Babajew D, Finkin S, Viant C, Gaebler C, Hoffmann HH, Barnes CO, Cipolla M, Ramos V, Oliveira TY, Cho A, Schmidt F, da Silva J, Bednarski E, Aguado L, Yee J, Daga M, Turroja M, Millard KG, Jankovic M, Gazumyan A, Zhao Z, Rice CM, Bieniasz PD, Caskey M, Hatziioannou T, Nussenzweig MC. Wang Z, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2021 Jun 2:2021.05.07.443175. doi: 10.1101/2021.05.07.443175. bioRxiv. 2021. Update in: Nature. 2021 Jul;595(7867):426-431. doi: 10.1038/s41586-021-03696-9 PMID: 34100013 Free PMC article. Updated. Preprint.
Plasma neutralization properties of the SARS-CoV-2 Omicron variant.
Schmidt F, Muecksch F, Weisblum Y, Da Silva J, Bednarski E, Cho A, Wang Z, Gaebler C, Caskey M, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Schmidt F, et al. Among authors: nussenzweig mc. medRxiv [Preprint]. 2021 Dec 13:2021.12.12.21267646. doi: 10.1101/2021.12.12.21267646. medRxiv. 2021. Update in: N Engl J Med. 2022 Feb 10;386(6):599-601. doi: 10.1056/NEJMc2119641 PMID: 34931199 Free PMC article. Updated. Preprint.
Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins.
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann HH, Ramos V, Zong S, Cipolla M, Johnson B, Schmidt F, DaSilva J, Bednarski E, Tanfous TB, Raspe R, Yao K, Lee YE, Chen T, Turroja M, Milard KG, Dizon J, Kaczynska A, Gazumyan A, Oliveira TY, Rice CM, Caskey M, Bieniasz PD, Hatziioannou T, Barnes CO, Nussenzweig MC. Wang Z, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2022 Feb 1:2022.02.01.478695. doi: 10.1101/2022.02.01.478695. bioRxiv. 2022. Update in: Immunity. 2022 Jun 14;55(6):998-1012.e8. doi: 10.1016/j.immuni.2022.04.003 PMID: 35132412 Free PMC article. Updated. Preprint.
Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose.
Muecksch F, Wang Z, Cho A, Gaebler C, Tanfous TB, DaSilva J, Bednarski E, Ramos V, Zong S, Johnson B, Raspe R, Schaefer-Babajew D, Shimeliovich I, Daga M, Yao KH, Schmidt F, Millard KG, Turroja M, Jankovic M, Oliveria TY, Gazumyan A, Caskey M, Hatziioannou T, Bieniasz PD, Nussenzweig MC. Muecksch F, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2022 Feb 15:2022.02.14.480394. doi: 10.1101/2022.02.14.480394. bioRxiv. 2022. PMID: 35194607 Free PMC article. Preprint.
Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape.
Witte L, Baharani V, Schmidt F, Wang Z, Cho A, Raspe R, Guzman-Cardozo MC, Muecksch F, Gaebler C, Caskey M, Nussenzweig MC, Hatziioannou T, Bieniasz PD. Witte L, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2022 Aug 19:2022.08.17.504313. doi: 10.1101/2022.08.17.504313. bioRxiv. 2022. Update in: Nat Commun. 2023 Jan 19;14(1):302. doi: 10.1038/s41467-023-35927-0 PMID: 36032981 Free PMC article. Updated. Preprint.
Antigen presentation dynamics shape the response to emergent variants like SARS-CoV-2 Omicron strain after multiple vaccinations with wild type strain.
Yang L, Van Beek M, Wang Z, Muecksch F, Canis M, Hatziioannou T, Bieniasz PD, Nussenzweig MC, Chakraborty AK. Yang L, et al. Among authors: nussenzweig mc. bioRxiv [Preprint]. 2022 Aug 25:2022.08.24.505127. doi: 10.1101/2022.08.24.505127. bioRxiv. 2022. Update in: Cell Rep. 2023 Apr 25;42(4):112256. doi: 10.1016/j.celrep.2023.112256 PMID: 36052368 Free PMC article. Updated. Preprint.
474 results