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Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release.
Narita T, Ito S, Higashijima Y, Chu WK, Neumann K, Walter J, Satpathy S, Liebner T, Hamilton WB, Maskey E, Prus G, Shibata M, Iesmantavicius V, Brickman JM, Anastassiadis K, Koseki H, Choudhary C. Narita T, et al. Among authors: higashijima y. Mol Cell. 2021 May 20;81(10):2166-2182.e6. doi: 10.1016/j.molcel.2021.03.008. Epub 2021 Mar 24. Mol Cell. 2021. PMID: 33765415 Free article.
Lysine demethylase 2B regulates angiogenesis via Jumonji C dependent suppression of angiogenic transcription factors.
Sasaki Y, Higashijima Y, Suehiro JI, Sugasawa T, Oguri-Nakamura E, Fukuhara S, Nagai N, Hirakawa Y, Wada Y, Nangaku M, Kanki Y. Sasaki Y, et al. Among authors: higashijima y. Biochem Biophys Res Commun. 2022 May 21;605:16-23. doi: 10.1016/j.bbrc.2022.03.054. Epub 2022 Mar 12. Biochem Biophys Res Commun. 2022. PMID: 35306360 Free article.
Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.
Higashijima Y, Matsui Y, Shimamura T, Nakaki R, Nagai N, Tsutsumi S, Abe Y, Link VM, Osaka M, Yoshida M, Watanabe R, Tanaka T, Taguchi A, Miura M, Ruan X, Li G, Inoue T, Nangaku M, Kimura H, Furukawa T, Aburatani H, Wada Y, Ruan Y, Glass CK, Kanki Y. Higashijima Y, et al. EMBO J. 2020 Apr 1;39(7):e103949. doi: 10.15252/embj.2019103949. Epub 2020 Mar 3. EMBO J. 2020. PMID: 32125007 Free PMC article.
27 results