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Page 1
Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice.
Chang J, Koseki M, Saga A, Kanno K, Higo T, Okuzaki D, Okada T, Inui H, Tanaka K, Asaji M, Zhu Y, Kamada Y, Ono M, Saibara T, Ichi I, Ohama T, Nishida M, Yamashita S, Sakata Y. Chang J, et al. Among authors: higo t. Front Endocrinol (Lausanne). 2021 Mar 10;11:614692. doi: 10.3389/fendo.2020.614692. eCollection 2020. Front Endocrinol (Lausanne). 2021. PMID: 33776901 Free PMC article.
Adeno-associated virus-mediated gene delivery promotes S-phase entry-independent precise targeted integration in cardiomyocytes.
Kohama Y, Higo S, Masumura Y, Shiba M, Kondo T, Ishizu T, Higo T, Nakamura S, Kameda S, Tabata T, Inoue H, Motooka D, Okuzaki D, Takashima S, Miyagawa S, Sawa Y, Hikoso S, Sakata Y. Kohama Y, et al. Among authors: higo s, higo t. Sci Rep. 2020 Sep 18;10(1):15348. doi: 10.1038/s41598-020-72216-y. Sci Rep. 2020. PMID: 32948788 Free PMC article.
Pemafibrate suppresses NLRP3 inflammasome activation in the liver and heart in a novel mouse model of steatohepatitis-related cardiomyopathy.
Kanno K, Koseki M, Chang J, Saga A, Inui H, Okada T, Tanaka K, Asaji M, Zhu Y, Ide S, Saito S, Higo T, Okuzaki D, Ohama T, Nishida M, Kamada Y, Ono M, Saibara T, Yamashita S, Sakata Y. Kanno K, et al. Among authors: higo t. Sci Rep. 2022 Feb 22;12(1):2996. doi: 10.1038/s41598-022-06542-8. Sci Rep. 2022. PMID: 35194060 Free PMC article.
A Dietary Oxysterol, 7-Ketocholesterol, Exacerbates Imiquimod-Induced Psoriasis-like Dermatitis in Steatohepatitic Mice.
Saga A, Koseki M, Kanno K, Chang J, Higo T, Okuzaki D, Okada T, Inui H, Asaji M, Tanaka K, Omatsu T, Nishihara S, Zhu Y, Ito K, Hattori H, Ichi I, Kamada Y, Ono M, Saibara T, Ohama T, Hikoso S, Nishida M, Yamashita S, Sakata Y. Saga A, et al. Among authors: higo t. Int J Mol Sci. 2022 Dec 13;23(24):15855. doi: 10.3390/ijms232415855. Int J Mol Sci. 2022. PMID: 36555497 Free PMC article.
Twin Study: The Factors Affecting the Serum LDL-C and HDL-C Levels and an RNA-Seq Analysis in Mononuclear Cells in Monozygotic Twins.
Nishihara S, Koseki M, Tanaka K, Omatsu T, Sawabe H, Inui H, Saga A, Okada T, Higo T, Ohama T, Nishida M, Sakata Y, Watanabe M; Osaka Twin Research Group. Nishihara S, et al. Among authors: higo t. J Atheroscler Thromb. 2024 Apr 27. doi: 10.5551/jat.64882. Online ahead of print. J Atheroscler Thromb. 2024. PMID: 38684403 Free article.
Generation of Induced Pluripotent Stem Cells From Patients With Duchenne Muscular Dystrophy and Their Induction to Cardiomyocytes.
Hashimoto A, Naito AT, Lee JK, Kitazume-Taneike R, Ito M, Yamaguchi T, Nakata R, Sumida T, Okada K, Nakagawa A, Higo T, Kuramoto Y, Sakai T, Tominaga K, Okinaga T, Kogaki S, Ozono K, Miyagawa S, Sawa Y, Sakata Y, Morita H, Umezawa A, Komuro I. Hashimoto A, et al. Among authors: higo t. Int Heart J. 2016;57(1):112-7. doi: 10.1536/ihj.15-376. Epub 2015 Dec 17. Int Heart J. 2016. PMID: 26673445 Free article.
Activation of endothelial β-catenin signaling induces heart failure.
Nakagawa A, Naito AT, Sumida T, Nomura S, Shibamoto M, Higo T, Okada K, Sakai T, Hashimoto A, Kuramoto Y, Oka T, Lee JK, Harada M, Ueda K, Shiojima I, Limbourg FP, Adams RH, Noda T, Sakata Y, Akazawa H, Komuro I. Nakagawa A, et al. Among authors: higo t. Sci Rep. 2016 May 5;6:25009. doi: 10.1038/srep25009. Sci Rep. 2016. PMID: 27146149 Free PMC article.
DNA single-strand break-induced DNA damage response causes heart failure.
Higo T, Naito AT, Sumida T, Shibamoto M, Okada K, Nomura S, Nakagawa A, Yamaguchi T, Sakai T, Hashimoto A, Kuramoto Y, Ito M, Hikoso S, Akazawa H, Lee JK, Shiojima I, McKinnon PJ, Sakata Y, Komuro I. Higo T, et al. Nat Commun. 2017 Apr 24;8:15104. doi: 10.1038/ncomms15104. Nat Commun. 2017. PMID: 28436431 Free PMC article.
Generation of Fabry cardiomyopathy model for drug screening using induced pluripotent stem cell-derived cardiomyocytes from a female Fabry patient.
Kuramoto Y, Naito AT, Tojo H, Sakai T, Ito M, Shibamoto M, Nakagawa A, Higo T, Okada K, Yamaguchi T, Lee JK, Miyagawa S, Sawa Y, Sakata Y, Komuro I. Kuramoto Y, et al. Among authors: higo t. J Mol Cell Cardiol. 2018 Aug;121:256-265. doi: 10.1016/j.yjmcc.2018.07.246. Epub 2018 Jul 23. J Mol Cell Cardiol. 2018. PMID: 30048710
212 results