Convertino M - Search Results

1

Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms.

Muralidharan A, Samoshkin A, Convertino M, Piltonen MH, Gris P, Wang J, Jiang C, Klares R 3rd, Linton A, Ji RR, Maixner W, Dokholyan NV, Mogil JS, Diatchenko L. Muralidharan A, et al. Among authors: convertino m. Br J Pharmacol. 2021 Jul;178(13):2709-2726. doi: 10.1111/bph.15463. Epub 2021 Apr 30. Br J Pharmacol. 2021. PMID: 33782947 Free PMC article.

2

μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids.

Convertino M, Samoshkin A, Gauthier J, Gold MS, Maixner W, Dokholyan NV, Diatchenko L. Convertino M, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Oct 1;62:61-7. doi: 10.1016/j.pnpbp.2014.11.009. Epub 2014 Dec 6. Prog Neuropsychopharmacol Biol Psychiatry. 2015. PMID: 25485963 Free PMC article. Review.

3

Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation.

Convertino M, Samoshkin A, Viet CT, Gauthier J, Li Fraine SP, Sharif-Naeini R, Schmidt BL, Maixner W, Diatchenko L, Dokholyan NV. Convertino M, et al. PLoS One. 2015 Nov 10;10(11):e0142826. doi: 10.1371/journal.pone.0142826. eCollection 2015. PLoS One. 2015. PMID: 26554831 Free PMC article.

4

Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling.

Samoshkin A, Convertino M, Viet CT, Wieskopf JS, Kambur O, Marcovitz J, Patel P, Stone LS, Kalso E, Mogil JS, Schmidt BL, Maixner W, Dokholyan NV, Diatchenko L. Samoshkin A, et al. Among authors: convertino m. Sci Rep. 2015 Dec 11;5:18198. doi: 10.1038/srep18198. Sci Rep. 2015. PMID: 26657998 Free PMC article.

5

Stabilization of μ-opioid receptor facilitates its cellular translocation and signaling.

Zhu C, Han Q, Samoshkin A, Convertino M, Linton A, Faison EM, Ji RR, Diatchenko L, Dokholyan NV. Zhu C, et al. Among authors: convertino m. Proteins. 2019 Oct;87(10):878-884. doi: 10.1002/prot.25751. Epub 2019 Jun 12. Proteins. 2019. PMID: 31141214 Free PMC article.

6

Differences in the Antinociceptive Effects and Binding Properties of Propranolol and Bupranolol Enantiomers.

Martin LJ, Piltonen MH, Gauthier J, Convertino M, Acland EL, Dokholyan NV, Mogil JS, Diatchenko L, Maixner W. Martin LJ, et al. Among authors: convertino m. J Pain. 2015 Dec;16(12):1321-1333. doi: 10.1016/j.jpain.2015.09.004. Epub 2015 Oct 9. J Pain. 2015. PMID: 26456674 Free article.

7

Computational Modeling of Small Molecule Ligand Binding Interactions and Affinities.

Convertino M, Dokholyan NV. Convertino M, et al. Methods Mol Biol. 2016;1414:23-32. doi: 10.1007/978-1-4939-3569-7_2. Methods Mol Biol. 2016. PMID: 27094283

8

Pharmacological Chaperones: Design and Development of New Therapeutic Strategies for the Treatment of Conformational Diseases.

Convertino M, Das J, Dokholyan NV. Convertino M, et al. ACS Chem Biol. 2016 Jun 17;11(6):1471-89. doi: 10.1021/acschembio.6b00195. Epub 2016 Apr 28. ACS Chem Biol. 2016. PMID: 27097127 Review.

9

miRNA-711 Binds and Activates TRPA1 Extracellularly to Evoke Acute and Chronic Pruritus.

Han Q, Liu D, Convertino M, Wang Z, Jiang C, Kim YH, Luo X, Zhang X, Nackley A, Dokholyan NV, Ji RR. Han Q, et al. Among authors: convertino m. Neuron. 2018 Aug 8;99(3):449-463.e6. doi: 10.1016/j.neuron.2018.06.039. Epub 2018 Jul 19. Neuron. 2018. PMID: 30033153 Free PMC article.

10

ApoE4-specific Misfolded Intermediate Identified by Molecular Dynamics Simulations.

Williams B 2nd, Convertino M, Das J, Dokholyan NV. Williams B 2nd, et al. Among authors: convertino m. PLoS Comput Biol. 2015 Oct 27;11(10):e1004359. doi: 10.1371/journal.pcbi.1004359. eCollection 2015 Oct. PLoS Comput Biol. 2015. PMID: 26506597 Free PMC article.

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