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Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health.
Ribo S, Sánchez-Infantes D, Martinez-Guino L, García-Mantrana I, Ramon-Krauel M, Tondo M, Arning E, Nofrarías M, Osorio-Conles Ó, Fernández-Pérez A, González-Torres P, Cebrià J, Gavaldà-Navarro A, Chenoll E, Isganaitis E, Villarroya F, Vallejo M, Segalés J, Jiménez-Chillarón JC, Bottiglieri T, Demerath EW, Fields DA, Collado MC, Lerin C. Ribo S, et al. Among authors: isganaitis e. Sci Transl Med. 2021 Mar 31;13(587):eabb0322. doi: 10.1126/scitranslmed.abb0322. Sci Transl Med. 2021. PMID: 33790021 Free PMC article.
Insights from rare variants into the genetic architecture and biology of youth-onset type 2 diabetes.
Kwak SH, Srinivasan S, Chen L, Todd J, Mercader J, Jensen E, Divers J, Mottl A, Pihoker C, Gandica R, Laffel L, Isganaitis E, Haymond M, Levitsky L, Pollin T, Florez J, Flannick J. Kwak SH, et al. Among authors: isganaitis e. Res Sq [Preprint]. 2023 May 18:rs.3.rs-2886343. doi: 10.21203/rs.3.rs-2886343/v1. Res Sq. 2023. Update in: Nat Metab. 2024 Feb;6(2):226-237. doi: 10.1038/s42255-023-00970-0 PMID: 37292813 Free PMC article. Updated. Preprint.
Efficacy and Safety of a Tubeless AID System Compared With Pump Therapy With CGM in the Treatment of Type 1 Diabetes in Adults With Suboptimal Glycemia: A Randomized, Parallel-Group Clinical Trial.
Renard E, Weinstock RS, Aleppo G, Bode BW, Brown SA, Castorino K, Hirsch IB, Kipnes MS, Laffel LM, Lal RA, Penfornis A, Riveline JP, Shah VN, Thivolet C, Ly TT; OP5-003 Research Group. Renard E, et al. Diabetes Care. 2024 Dec 1;47(12):2248-2257. doi: 10.2337/dc24-1550. Diabetes Care. 2024. PMID: 39423118 Free PMC article. Clinical Trial.
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism.
Lerin C, Goldfine AB, Boes T, Liu M, Kasif S, Dreyfuss JM, De Sousa-Coelho AL, Daher G, Manoli I, Sysol JR, Isganaitis E, Jessen N, Goodyear LJ, Beebe K, Gall W, Venditti CP, Patti ME. Lerin C, et al. Among authors: isganaitis e. Mol Metab. 2016 Aug 6;5(10):926-936. doi: 10.1016/j.molmet.2016.08.001. eCollection 2016 Oct. Mol Metab. 2016. PMID: 27689005 Free PMC article.
Brown Fat-Activating Lipokine 12,13-diHOME in Human Milk Is Associated With Infant Adiposity.
Wolfs D, Lynes MD, Tseng YH, Pierce S, Bussberg V, Darkwah A, Tolstikov V, Narain NR, Rudolph MC, Kiebish MA, Demerath EW, Fields DA, Isganaitis E. Wolfs D, et al. Among authors: isganaitis e. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e943-e956. doi: 10.1210/clinem/dgaa799. J Clin Endocrinol Metab. 2021. PMID: 33135728 Free PMC article.
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