Epigenetic programming at the Mogat1 locus may link neonatal overnutrition with long-term hepatic steatosis and insulin resistance.
Ramon-Krauel M, Pentinat T, Bloks VW, Cebrià J, Ribo S, Pérez-Wienese R, Vilà M, Palacios-Marin I, Fernández-Pérez A, Vallejo M, Téllez N, Rodríguez MÀ, Yanes O, Lerin C, Díaz R, Plosch T, Tietge UJF, Jimenez-Chillaron JC.
Ramon-Krauel M, et al. Among authors: vallejo m.
FASEB J. 2018 May 29:fj201700717RR. doi: 10.1096/fj.201700717RR. Online ahead of print.
FASEB J. 2018.
PMID: 29812971
Our data suggest that targeting hepatic monoacylglycerol acyltransferase activity during early life might provide a novel strategy to improve hepatic insulin sensitivity and prevent late-onset insulin resistance and fatty liver disease.-Ramon-Krauel, M., Pentinat, T., Blok …
Our data suggest that targeting hepatic monoacylglycerol acyltransferase activity during early life might provide a novel strategy to improv …