Bianchi G - Search Results

1

SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathy.

Torre E, Arici M, Lodrini AM, Ferrandi M, Barassi P, Hsu SC, Chang GJ, Boz E, Sala E, Vagni S, Altomare C, Mostacciuolo G, Bussadori C, Ferrari P, Bianchi G, Rocchetti M. Torre E, et al. Among authors: bianchi g. Cardiovasc Res. 2022 Mar 16;118(4):1020-1032. doi: 10.1093/cvr/cvab123. Cardiovasc Res. 2022. PMID: 33792692 Free PMC article.

2

Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure.

Luraghi A, Ferrandi M, Barassi P, Arici M, Hsu SC, Torre E, Ronchi C, Romerio A, Chang GJ, Ferrari P, Bianchi G, Zaza A, Rocchetti M, Peri F. Luraghi A, et al. Among authors: bianchi g. J Med Chem. 2022 May 26;65(10):7324-7333. doi: 10.1021/acs.jmedchem.2c00347. Epub 2022 May 17. J Med Chem. 2022. PMID: 35580334 Free PMC article.

3

Istaroxime, a stimulator of sarcoplasmic reticulum calcium adenosine triphosphatase isoform 2a activity, as a novel therapeutic approach to heart failure.

Micheletti R, Palazzo F, Barassi P, Giacalone G, Ferrandi M, Schiavone A, Moro B, Parodi O, Ferrari P, Bianchi G. Micheletti R, et al. Among authors: bianchi g. Am J Cardiol. 2007 Jan 22;99(2A):24A-32A. doi: 10.1016/j.amjcard.2006.09.003. Epub 2006 Sep 25. Am J Cardiol. 2007. PMID: 17239701

4

Istaroxime stimulates SERCA2a and accelerates calcium cycling in heart failure by relieving phospholamban inhibition.

Ferrandi M, Barassi P, Tadini-Buoninsegni F, Bartolommei G, Molinari I, Tripodi MG, Reina C, Moncelli MR, Bianchi G, Ferrari P. Ferrandi M, et al. Among authors: bianchi g. Br J Pharmacol. 2013 Aug;169(8):1849-61. doi: 10.1111/bph.12278. Br J Pharmacol. 2013. PMID: 23763364 Free PMC article.

5

Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function.

Arici M, Ferrandi M, Barassi P, Hsu SC, Torre E, Luraghi A, Ronchi C, Chang GJ, Peri F, Ferrari P, Bianchi G, Rocchetti M, Zaza A. Arici M, et al. Among authors: bianchi g. J Pharmacol Exp Ther. 2023 Jan;384(1):231-244. doi: 10.1124/jpet.122.001335. Epub 2022 Sep 24. J Pharmacol Exp Ther. 2023. PMID: 36153005 Free article.

6

PST 2238: a new antihypertensive compound that modulates renal Na-K pump function without diuretic activity in Milan hypertensive rats.

Ferrandi M, Barassi P, Minotti E, Duzzi L, Molinari I, Bianchi G, Ferrari P. Ferrandi M, et al. Among authors: bianchi g. J Cardiovasc Pharmacol. 2002 Dec;40(6):881-9. doi: 10.1097/00005344-200212000-00009. J Cardiovasc Pharmacol. 2002. PMID: 12451321

7

Targeting Ouabain- and Adducin-dependent mechanisms of hypertension and cardiovascular remodeling as a novel pharmacological approach.

Ferrari P, Ferrandi M, Valentini G, Manunta P, Bianchi G. Ferrari P, et al. Among authors: bianchi g. Med Hypotheses. 2007;68(6):1307-14. doi: 10.1016/j.mehy.2006.07.058. Epub 2006 Nov 9. Med Hypotheses. 2007. PMID: 17097240

8

Characteristics of a ouabain-like factor from Milan hypertensive rats.

Ferrandi M, Minotti E, Salardi S, Florio M, Bianchi G, Ferrari P. Ferrandi M, et al. Among authors: bianchi g. J Cardiovasc Pharmacol. 1993;22 Suppl 2:S75-8. doi: 10.1097/00005344-199322002-00024. J Cardiovasc Pharmacol. 1993. PMID: 7508036

9

Genetic mapping and tailored antihypertensive therapy.

Ferrari P, Bianchi G. Ferrari P, et al. Among authors: bianchi g. Cardiovasc Drugs Ther. 2000 Aug;14(4):387-95. doi: 10.1023/a:1007860115489. Cardiovasc Drugs Ther. 2000. PMID: 10999645 Review.

10

Targeting SERCA2a as an innovative approach to the therapy of congestive heart failure.

Ferrari P, Micheletti R, Valentini G, Bianchi G. Ferrari P, et al. Among authors: bianchi g. Med Hypotheses. 2007;68(5):1120-5. doi: 10.1016/j.mehy.2006.08.045. Epub 2006 Nov 17. Med Hypotheses. 2007. PMID: 17113239

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