MacFadden A - Search Results

1

An expanded class of histidine-accepting viral tRNA-like structures.

Langeberg CJ, Sherlock ME, MacFadden A, Kieft JS. Langeberg CJ, et al. Among authors: macfadden a. RNA. 2021 Jun;27(6):653-664. doi: 10.1261/rna.078550.120. Epub 2021 Apr 2. RNA. 2021. PMID: 33811147 Free PMC article.

2

Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs.

MacFadden A, O'Donoghue Z, Silva PAGC, Chapman EG, Olsthoorn RC, Sterken MG, Pijlman GP, Bredenbeek PJ, Kieft JS. MacFadden A, et al. Nat Commun. 2018 Jan 9;9(1):119. doi: 10.1038/s41467-017-02604-y. Nat Commun. 2018. PMID: 29317714 Free PMC article.

3

Ribosome-induced RNA conformational changes in a viral 3'-UTR sense and regulate translation levels.

Hartwick EW, Costantino DA, MacFadden A, Nix JC, Tian S, Das R, Kieft JS. Hartwick EW, et al. Among authors: macfadden a. Nat Commun. 2018 Nov 29;9(1):5074. doi: 10.1038/s41467-018-07542-x. Nat Commun. 2018. PMID: 30498211 Free PMC article.

4

Structural diversity and phylogenetic distribution of valyl tRNA-like structures in viruses.

Sherlock ME, Hartwick EW, MacFadden A, Kieft JS. Sherlock ME, et al. Among authors: macfadden a. RNA. 2021 Jan;27(1):27-39. doi: 10.1261/rna.076968.120. Epub 2020 Oct 2. RNA. 2021. PMID: 33008837 Free PMC article.

5

A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure.

Bonilla SL, Sherlock ME, MacFadden A, Kieft JS. Bonilla SL, et al. Among authors: macfadden a. Science. 2021 Nov 19;374(6570):955-960. doi: 10.1126/science.abe8526. Epub 2021 Nov 18. Science. 2021. PMID: 34793227 Free PMC article.

6

An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by β-coronavirus Non-structural Protein 1.

Maurina SF, O'Sullivan JP, Sharma G, Pineda Rodriguez DC, MacFadden A, Cendali F, Henen MA, Vögeli B, Kieft JS, Glasgow A, Steckelberg AL. Maurina SF, et al. Among authors: macfadden a. J Mol Biol. 2023 Oct 15;435(20):168259. doi: 10.1016/j.jmb.2023.168259. Epub 2023 Sep 1. J Mol Biol. 2023. PMID: 37660941 Free PMC article.

7

Nanopore sequencing of internal 2'-PO₄ modifications installed by RNA repair.

White LK, Strugar SM, MacFadden A, Hesselberth JR. White LK, et al. Among authors: macfadden a. RNA. 2023 Jun;29(6):847-861. doi: 10.1261/rna.079290.122. Epub 2023 Feb 28. RNA. 2023. PMID: 36854608 Free PMC article.

8

Ubiquitin chain trimming recycles the substrate binding sites of the 26 S proteasome and promotes degradation of lysine 48-linked polyubiquitin conjugates.

Zhang NY, Jacobson AD, Macfadden A, Liu CW. Zhang NY, et al. Among authors: macfadden a. J Biol Chem. 2011 Jul 22;286(29):25540-6. doi: 10.1074/jbc.M111.260505. Epub 2011 Jun 1. J Biol Chem. 2011. PMID: 21632534 Free PMC article.

9

Autoregulation of the 26S proteasome by in situ ubiquitination.

Jacobson AD, MacFadden A, Wu Z, Peng J, Liu CW. Jacobson AD, et al. Among authors: macfadden a. Mol Biol Cell. 2014 Jun 15;25(12):1824-35. doi: 10.1091/mbc.E13-10-0585. Epub 2014 Apr 17. Mol Biol Cell. 2014. PMID: 24743594 Free PMC article.

10

Z-Form Adoption of Nucleic Acid is a Multi-Step Process Which Proceeds through a Melted Intermediate.

Nichols PJ, Krall JB, Henen MA, Welty R, Macfadden A, Vicens Q, Vögeli B. Nichols PJ, et al. Among authors: macfadden a. J Am Chem Soc. 2024 Jan 10;146(1):677-694. doi: 10.1021/jacs.3c10406. Epub 2023 Dec 22. J Am Chem Soc. 2024. PMID: 38131335 Free PMC article.

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