Shizu R - Search Results

1

Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug-induced liver injury.

Shimizu Y, Sasaki T, Yonekawa E, Yamazaki H, Ogura R, Watanabe M, Hosaka T, Shizu R, Takeshita JI, Yoshinari K. Shimizu Y, et al. Among authors: shizu r. J Toxicol Sci. 2021;46(4):167-176. doi: 10.2131/jts.46.167. J Toxicol Sci. 2021. PMID: 33814510 Free article.

2

Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.

Shizu R, Benoki S, Numakura Y, Kodama S, Miyata M, Yamazoe Y, Yoshinari K. Shizu R, et al. PLoS One. 2013 Apr 23;8(4):e61802. doi: 10.1371/journal.pone.0061802. Print 2013. PLoS One. 2013. PMID: 23626729 Free PMC article.

3

PXR stimulates growth factor-mediated hepatocyte proliferation by cross-talk with the FOXO transcription factor.

Shizu R, Abe T, Benoki S, Takahashi M, Kodama S, Miayata M, Matsuzawa A, Yoshinari K. Shizu R, et al. Biochem J. 2016 Feb 1;473(3):257-66. doi: 10.1042/BJ20150734. Epub 2015 Nov 16. Biochem J. 2016. PMID: 26574435

4

Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes.

Abe T, Amaike Y, Shizu R, Takahashi M, Kano M, Hosaka T, Sasaki T, Kodama S, Matsuzawa A, Yoshinari K. Abe T, et al. Among authors: shizu r. Toxicol Sci. 2018 Oct 1;165(2):408-419. doi: 10.1093/toxsci/kfy149. Toxicol Sci. 2018. PMID: 29893953

5

Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR.

Yoshimaru S, Shizu R, Tsuruta S, Amaike Y, Kano M, Hosaka T, Sasaki T, Yoshinari K. Yoshimaru S, et al. Among authors: shizu r. J Toxicol Sci. 2018;43(7):443-450. doi: 10.2131/jts.43.443. J Toxicol Sci. 2018. PMID: 29973476 Free article.

6

Possible involvement of the competition for the transcriptional coactivator glucocorticoid receptor-interacting protein 1 in the inflammatory signal-dependent suppression of PXR-mediated CYP3A induction in vitro.

Okamura M, Shizu R, Hosaka T, Sasaki T, Yoshinari K. Okamura M, et al. Among authors: shizu r. Drug Metab Pharmacokinet. 2019 Aug;34(4):272-279. doi: 10.1016/j.dmpk.2019.04.005. Epub 2019 Apr 19. Drug Metab Pharmacokinet. 2019. PMID: 31280915

7

Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism.

Abe T, Shizu R, Sasaki T, Shimizu Y, Hosaka T, Kodama S, Matsuzawa A, Yoshinari K. Abe T, et al. Among authors: shizu r. J Pharmacol Exp Ther. 2019 Dec;371(3):590-601. doi: 10.1124/jpet.119.258632. Epub 2019 Sep 18. J Pharmacol Exp Ther. 2019. PMID: 31533970

8

Application of cytochrome P450 reactivity on the characterization of chemical compounds and its association with repeated-dose toxicity.

Watanabe M, Sasaki T, Takeshita JI, Kushida M, Shimizu Y, Oki H, Kitsunai Y, Nakayama H, Saruhashi H, Ogura R, Shizu R, Hosaka T, Yoshinari K. Watanabe M, et al. Among authors: shizu r. Toxicol Appl Pharmacol. 2020 Feb 1;388:114854. doi: 10.1016/j.taap.2019.114854. Epub 2019 Dec 10. Toxicol Appl Pharmacol. 2020. PMID: 31836524

9

Nuclear receptor CAR-mediated liver cancer and its species differences.

Shizu R, Yoshinari K. Shizu R, et al. Expert Opin Drug Metab Toxicol. 2020 Apr;16(4):343-351. doi: 10.1080/17425255.2020.1746268. Epub 2020 Mar 26. Expert Opin Drug Metab Toxicol. 2020. PMID: 32202166 Review.

10

Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor α and Peroxisome Proliferator-Activated Receptor γ Coactivator 1α-Dependent Gene Expression to Increase Blood Triglyceride Levels.

Shizu R, Otsuka Y, Ezaki K, Ishii C, Arakawa S, Amaike Y, Abe T, Hosaka T, Sasaki T, Kanno Y, Miyata M, Yamazoe Y, Yoshinari K. Shizu R, et al. Mol Pharmacol. 2020 Nov;98(5):634-647. doi: 10.1124/molpharm.120.000103. Epub 2020 Sep 5. Mol Pharmacol. 2020. PMID: 32892155

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

36 results

Search Page

Filters