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Butyrolactol A is a phospholipid flippase inhibitor that potentiates the bioactivity of caspofungin against resistant fungi.
Chen X, Duan HD, Hoy MJ, Koteva K, Spitzer M, Guitor AK, Puumala E, Hu G, Yiu B, Chou S, Bian Z, Guo ABY, Sun S, Robbins N, Cook MA, Truant R, MacNeil LT, Brown ED, Kronstad JW, Cowen LE, Heitman J, Li H, Wright GD. Chen X, et al. Among authors: guo aby. bioRxiv [Preprint]. 2025 Jan 6:2025.01.06.630955. doi: 10.1101/2025.01.06.630955. bioRxiv. 2025. PMID: 39829750 Free PMC article. Preprint.
A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in Escherichia coli.
Rachwalski K, Madden SJ, Ritchie N, French S, Bhando T, Girgis-Gabardo A, Tu M, Gordzevich R, Ives R, Guo ABY, Johnson JW, Xu Y, Kapadia SB, Magolan J, Brown ED. Rachwalski K, et al. Among authors: guo aby. iScience. 2024 Sep 5;27(10):110894. doi: 10.1016/j.isci.2024.110894. eCollection 2024 Oct 18. iScience. 2024. PMID: 39376497 Free PMC article.
Deep learning guided design of dynamic proteins.
Guo AB, Akpinaroglu D, Kelly MJS, Kortemme T. Guo AB, et al. bioRxiv [Preprint]. 2024 Jul 19:2024.07.17.603962. doi: 10.1101/2024.07.17.603962. bioRxiv. 2024. PMID: 39071443 Free PMC article. Preprint.
Design principles of protein switches.
Alberstein RG, Guo AB, Kortemme T. Alberstein RG, et al. Among authors: guo ab. Curr Opin Struct Biol. 2022 Feb;72:71-78. doi: 10.1016/j.sbi.2021.08.004. Epub 2021 Sep 16. Curr Opin Struct Biol. 2022. PMID: 34537489 Free PMC article. Review.
14 results