Heine H - Search Results

1

Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics.

Heine H, Adanitsch F, Peternelj TT, Haegman M, Kasper C, Ittig S, Beyaert R, Jerala R, Zamyatina A. Heine H, et al. Front Immunol. 2021 Mar 18;12:631797. doi: 10.3389/fimmu.2021.631797. eCollection 2021. Front Immunol. 2021. PMID: 33815382 Free PMC article.

2

Investigation on the agonistic and antagonistic biological activities of synthetic Chlamydia lipid A and its use in in vitro enzymatic assays.

Heine H, Gronow S, Zamyatina A, Kosma P, Brade H. Heine H, et al. J Endotoxin Res. 2007;13(2):126-32. doi: 10.1177/0968051907079122. J Endotoxin Res. 2007. PMID: 17621554

3

Anti-endotoxic activity and structural basis for human MD-2·TLR4 antagonism of tetraacylated lipid A mimetics based on βGlcN(1↔1)αGlcN scaffold.

Garate JA, Stöckl J, Fernández-Alonso Mdel C, Artner D, Haegman M, Oostenbrink C, Jiménez-Barbero J, Beyaert R, Heine H, Kosma P, Zamyatina A. Garate JA, et al. Among authors: heine h. Innate Immun. 2015 Jul;21(5):490-503. doi: 10.1177/1753425914550426. Epub 2014 Nov 13. Innate Immun. 2015. PMID: 25394365 Free PMC article.

4

The Human-Associated Archaeon Methanosphaera stadtmanae Is Recognized through Its RNA and Induces TLR8-Dependent NLRP3 Inflammasome Activation.

Vierbuchen T, Bang C, Rosigkeit H, Schmitz RA, Heine H. Vierbuchen T, et al. Among authors: heine h. Front Immunol. 2017 Nov 13;8:1535. doi: 10.3389/fimmu.2017.01535. eCollection 2017. Front Immunol. 2017. PMID: 29181003 Free PMC article.

5

Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics.

Adanitsch F, Shi J, Shao F, Beyaert R, Heine H, Zamyatina A. Adanitsch F, et al. Among authors: heine h. Chem Sci. 2018 Mar 15;9(16):3957-3963. doi: 10.1039/c7sc05323a. eCollection 2018 Apr 28. Chem Sci. 2018. PMID: 29780528 Free PMC article.

6

Disaccharide-Based Anionic Amphiphiles as Potent Inhibitors of Lipopolysaccharide-Induced Inflammation.

Borio A, Holgado A, Garate JA, Beyaert R, Heine H, Zamyatina A. Borio A, et al. Among authors: heine h. ChemMedChem. 2018 Nov 6;13(21):2317-2331. doi: 10.1002/cmdc.201800505. Epub 2018 Oct 23. ChemMedChem. 2018. PMID: 30276970

7

Lipophilic Allergens, Different Modes of Allergen-Lipid Interaction and Their Impact on Asthma and Allergy.

Jappe U, Schwager C, Schromm AB, González Roldán N, Stein K, Heine H, Duda KA. Jappe U, et al. Among authors: heine h. Front Immunol. 2019 Feb 14;10:122. doi: 10.3389/fimmu.2019.00122. eCollection 2019. Front Immunol. 2019. PMID: 30837983 Free PMC article. Review.

8

Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways.

Zamyatina A, Heine H. Zamyatina A, et al. Among authors: heine h. Front Immunol. 2020 Nov 27;11:585146. doi: 10.3389/fimmu.2020.585146. eCollection 2020. Front Immunol. 2020. PMID: 33329561 Free PMC article. Review.

9

Corrigendum: Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways.

Zamyatina A, Heine H. Zamyatina A, et al. Among authors: heine h. Front Immunol. 2021 Jan 28;12:649442. doi: 10.3389/fimmu.2021.649442. eCollection 2021. Front Immunol. 2021. PMID: 33584736 Free PMC article.

10

Lipid A Mimetics Based on Unnatural Disaccharide Scaffold as Potent TLR4 Agonists for Prospective Immunotherapeutics and Adjuvants.

Strobl S, Hofbauer K, Heine H, Zamyatina A. Strobl S, et al. Among authors: heine h. Chemistry. 2022 Jun 21;28(35):e202200547. doi: 10.1002/chem.202200547. Epub 2022 May 11. Chemistry. 2022. PMID: 35439332 Free PMC article.

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