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Page 1
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Participants E, Barna M, Das R. Leppek K, et al. Among authors: choe c. bioRxiv [Preprint]. 2021 Mar 30:2021.03.29.437587. doi: 10.1101/2021.03.29.437587. bioRxiv. 2021. Update in: Nat Commun. 2022 Mar 22;13(1):1536. doi: 10.1038/s41467-022-28776-w PMID: 33821271 Free PMC article. Updated. Preprint.
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Wayment-Steele HK, Kim DS, Choe CA, Nicol JJ, Wellington-Oguri R, Watkins AM, Sperberg RAP, Huang PS, Participants E, Das R. Wayment-Steele HK, et al. bioRxiv [Preprint]. 2021 Feb 19:2020.08.22.262931. doi: 10.1101/2020.08.22.262931. bioRxiv. 2021. Update in: Nucleic Acids Res. 2021 Oct 11;49(18):10604-10617. doi: 10.1093/nar/gkab764 PMID: 32869022 Free PMC article. Updated. Preprint.
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Diaz F, Cai H, Guo P, Wu J, Meng F, Shi S, Participants E, Dormitzer PR, Solórzano A, Barna M, Das R. Leppek K, et al. Among authors: choe c. Nat Commun. 2022 Mar 22;13(1):1536. doi: 10.1038/s41467-022-28776-w. Nat Commun. 2022. PMID: 35318324 Free PMC article.
Compact RNA sensors for increasingly complex functions of multiple inputs.
Choe C, Andreasson JOL, Melaine F, Kladwang W, Wu MJ, Portela F, Wellington-Oguri R, Nicol JJ, Wayment-Steele HK, Gotrik M, Participants E, Khatri P, Greenleaf WJ, Das R. Choe C, et al. bioRxiv [Preprint]. 2024 Jan 16:2024.01.04.572289. doi: 10.1101/2024.01.04.572289. bioRxiv. 2024. PMID: 38260323 Free PMC article. Preprint.
Ribonanza: deep learning of RNA structure through dual crowdsourcing.
He S, Huang R, Townley J, Kretsch RC, Karagianes TG, Cox DBT, Blair H, Penzar D, Vyaltsev V, Aristova E, Zinkevich A, Bakulin A, Sohn H, Krstevski D, Fukui T, Tatematsu F, Uchida Y, Jang D, Lee JS, Shieh R, Ma T, Martynov E, Shugaev MV, Bukhari HST, Fujikawa K, Onodera K, Henkel C, Ron S, Romano J, Nicol JJ, Nye GP, Wu Y, Choe C, Reade W; Eterna participants; Das R. He S, et al. Among authors: choe c. bioRxiv [Preprint]. 2024 Jun 11:2024.02.24.581671. doi: 10.1101/2024.02.24.581671. bioRxiv. 2024. PMID: 38464325 Free PMC article. Preprint.
Targeting peptide antigens using a multiallelic MHC I-binding system.
Du H, Mallik L, Hwang D, Sun Y, Kaku C, Hoces D, Sun SM, Ghinnagow R, Carro SD, Phan HAT, Gupta S, Blackson W, Lee H, Choe CA, Dersh D, Liu J, Bell B, Yang H, Papadaki GF, Young MC, Zhou E, El Nesr G, Goli KD, Eisenlohr LC, Minn AJ, Hernandez-Lopez RA, Jardine JG, Sgourakis NG, Huang PS. Du H, et al. Among authors: choe ca. Nat Biotechnol. 2024 Dec 13. doi: 10.1038/s41587-024-02505-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 39672954
296 results