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Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines.
Müller MA, Raj VS, Muth D, Meyer B, Kallies S, Smits SL, Wollny R, Bestebroer TM, Specht S, Suliman T, Zimmermann K, Binger T, Eckerle I, Tschapka M, Zaki AM, Osterhaus AD, Fouchier RA, Haagmans BL, Drosten C. Müller MA, et al. Among authors: bestebroer tm. mBio. 2012 Dec 11;3(6):e00515-12. doi: 10.1128/mBio.00515-12. mBio. 2012. PMID: 23232719 Free PMC article.
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment.
de Wilde AH, Raj VS, Oudshoorn D, Bestebroer TM, van Nieuwkoop S, Limpens RWAL, Posthuma CC, van der Meer Y, Bárcena M, Haagmans BL, Snijder EJ, van den Hoogen BG. de Wilde AH, et al. J Gen Virol. 2013 Aug;94(Pt 8):1749-1760. doi: 10.1099/vir.0.052910-0. Epub 2013 Apr 25. J Gen Virol. 2013. PMID: 23620378 Free PMC article.
Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus.
Raj VS, Smits SL, Provacia LB, van den Brand JM, Wiersma L, Ouwendijk WJ, Bestebroer TM, Spronken MI, van Amerongen G, Rottier PJ, Fouchier RA, Bosch BJ, Osterhaus AD, Haagmans BL. Raj VS, et al. J Virol. 2014 Feb;88(3):1834-8. doi: 10.1128/JVI.02935-13. Epub 2013 Nov 20. J Virol. 2014. PMID: 24257613 Free PMC article.
Asymptomatic Middle East respiratory syndrome coronavirus infection in rabbits.
Haagmans BL, van den Brand JM, Provacia LB, Raj VS, Stittelaar KJ, Getu S, de Waal L, Bestebroer TM, van Amerongen G, Verjans GM, Fouchier RA, Smits SL, Kuiken T, Osterhaus AD. Haagmans BL, et al. Among authors: bestebroer tm. J Virol. 2015 Jun;89(11):6131-5. doi: 10.1128/JVI.00661-15. Epub 2015 Mar 25. J Virol. 2015. PMID: 25810539 Free PMC article.
An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels.
Haagmans BL, van den Brand JM, Raj VS, Volz A, Wohlsein P, Smits SL, Schipper D, Bestebroer TM, Okba N, Fux R, Bensaid A, Solanes Foz D, Kuiken T, Baumgärtner W, Segalés J, Sutter G, Osterhaus AD. Haagmans BL, et al. Among authors: bestebroer tm. Science. 2016 Jan 1;351(6268):77-81. doi: 10.1126/science.aad1283. Epub 2015 Dec 17. Science. 2016. PMID: 26678878
Lack of Middle East Respiratory Syndrome Coronavirus Transmission in Rabbits.
Widagdo W, Okba NMA, Richard M, de Meulder D, Bestebroer TM, Lexmond P, Farag EABA, Al-Hajri M, Stittelaar KJ, de Waal L, van Amerongen G, van den Brand JMA, Haagmans BL, Herfst S. Widagdo W, et al. Viruses. 2019 Apr 24;11(4):381. doi: 10.3390/v11040381. Viruses. 2019. PMID: 31022948 Free PMC article.
Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model.
Rockx B, Kuiken T, Herfst S, Bestebroer T, Lamers MM, Oude Munnink BB, de Meulder D, van Amerongen G, van den Brand J, Okba NMA, Schipper D, van Run P, Leijten L, Sikkema R, Verschoor E, Verstrepen B, Bogers W, Langermans J, Drosten C, Fentener van Vlissingen M, Fouchier R, de Swart R, Koopmans M, Haagmans BL. Rockx B, et al. Among authors: bestebroer t. Science. 2020 May 29;368(6494):1012-1015. doi: 10.1126/science.abb7314. Epub 2020 Apr 17. Science. 2020. PMID: 32303590 Free PMC article.
SARS-CoV-2 is transmitted via contact and via the air between ferrets.
Richard M, Kok A, de Meulder D, Bestebroer TM, Lamers MM, Okba NMA, Fentener van Vlissingen M, Rockx B, Haagmans BL, Koopmans MPG, Fouchier RAM, Herfst S. Richard M, et al. Nat Commun. 2020 Jul 8;11(1):3496. doi: 10.1038/s41467-020-17367-2. Nat Commun. 2020. PMID: 32641684 Free PMC article.
130 results