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Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt).
Lugar CW, Clarke CA, Morphy R, Rudyk H, Sapmaz S, Stites RE, Vaught GM, Furness K, Broughton HB, Durst GL, Clawson DK, Stout SL, Guo SY, Durbin JD, Stayrook KR, Edmondson DD, Kikly K, New NE, Bina HA, Chambers MG, Shetler P, Chang WY, Chang VC, Barr R, Gough WH, Steele JP, Getman B, Patel N, Mathes BM, Richardson TI. Lugar CW, et al. Among authors: chang wy, chang vc. J Med Chem. 2021 May 13;64(9):5470-5484. doi: 10.1021/acs.jmedchem.0c01918. Epub 2021 Apr 14. J Med Chem. 2021. PMID: 33852312
A nondepleting anti-CD19 antibody impairs B cell function and inhibits autoimmune diseases.
Boyles JS, Sadowski D, Potter S, Vukojicic A, Parker J, Chang WY, Ma YL, Chambers MG, Nelson J, Barmettler B, Smith EM, Kersjes K, Himes ER, Lin C, Lucchesi J, Brahmbhatt J, Sina R, Martin JA, Maestri E, Wiethoff CM, Dyas GL, Linnik MD, Na S, Witcher DR, Budelsky A, Rubtsova K. Boyles JS, et al. Among authors: chang wy. JCI Insight. 2023 Jul 10;8(13):e166137. doi: 10.1172/jci.insight.166137. JCI Insight. 2023. PMID: 37427592 Free PMC article.
Serial changes in metabolic dysfunction-associated steatotic liver disease after sleeve gastrectomy and their associations with abdominal adiposity: a prospective cohort study.
Yang CY, Chen JH, Chen CY, Kao CY, Huang SF, Chang WY, Tu HP, Huang JF, Yu ML, Tai CM. Yang CY, et al. Among authors: chang wy. Surg Obes Relat Dis. 2024 Nov 29:S1550-7289(24)00908-0. doi: 10.1016/j.soard.2024.11.007. Online ahead of print. Surg Obes Relat Dis. 2024. PMID: 39706718
595 results