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Discovery of 2,4-1H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors.
Veerman JJN, Bruseker YB, Damen E, Heijne EH, van Bruggen W, Hekking KFW, Winkel R, Hupp CD, Keefe AD, Liu J, Thomson HA, Zhang Y, Cuozzo JW, McRiner AJ, Mulvihill MJ, van Rijnsbergen P, Zech B, Renzetti LM, Babiss L, Müller G. Veerman JJN, et al. Among authors: muller g. ACS Med Chem Lett. 2021 Mar 3;12(4):555-562. doi: 10.1021/acsmedchemlett.0c00547. eCollection 2021 Apr 8. ACS Med Chem Lett. 2021. PMID: 33859795 Free PMC article.
Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2.
Leenders R, Zijlmans R, van Bree B, van de Sande M, Trivarelli F, Damen E, Wegert A, Müller D, Ehlert JE, Feger D, Heidemann-Dinger C, Kubbutat M, Schächtele C, Lenstra DC, Mecinović J, Müller G. Leenders R, et al. Among authors: muller g, muller d. Bioorg Med Chem Lett. 2019 Sep 1;29(17):2516-2524. doi: 10.1016/j.bmcl.2019.06.012. Epub 2019 Jun 14. Bioorg Med Chem Lett. 2019. PMID: 31350126
Charting Biologically Relevant Spirocyclic Compound Space.
Müller G, Berkenbosch T, Benningshof JC, Stumpfe D, Bajorath J. Müller G, et al. Chemistry. 2017 Jan 12;23(3):703-710. doi: 10.1002/chem.201604714. Epub 2016 Dec 5. Chemistry. 2017. PMID: 27859909
NMR in target driven drug discovery: why not?
Keiffer S, Carneiro MG, Hollander J, Kobayashi M, Pogoryelev D, Ab E, Theisgen S, Müller G, Siegal G. Keiffer S, et al. Among authors: muller g. J Biomol NMR. 2020 Nov;74(10-11):521-529. doi: 10.1007/s10858-020-00343-9. Epub 2020 Sep 8. J Biomol NMR. 2020. PMID: 32901320 Free PMC article.
Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock.
Vignon P, Charron C, Legras A, Musset F, Slama M, Prat G, Silva S, Vandroux D, Müller G, Levy B, Boissier F, Evrard B, Goudelin M, Mankikian S, Nay MA, Jabot J, Riu B, Bailly P, Maizel J, Léger J, Vieillard-Baron A; CRICS-TRIGGERSEP Network. Vignon P, et al. Among authors: muller g. Intensive Care Med. 2025 Jan 7. doi: 10.1007/s00134-024-07748-2. Online ahead of print. Intensive Care Med. 2025. PMID: 39774865
Effectiveness and tolerability of lactic acid vaginal gel compared to oral metronidazole in the treatment of acute symptomatic bacterial vaginosis: a multicenter, randomized-controlled, head-to-head pilot study.
Tidbury F, Brülhart G, Müller G, Pavicic E, Weidlinger S, Eichner G, von Wolff M, Stute P. Tidbury F, et al. Among authors: muller g. BMC Womens Health. 2025 Jan 6;25(1):7. doi: 10.1186/s12905-024-03513-1. BMC Womens Health. 2025. PMID: 39762879 Free PMC article. Clinical Trial.
3,340 results