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Fibroblast-Specific Proteotranscriptomes Reveal Distinct Fibrotic Signatures of Human Sinoatrial Node in Nonfailing and Failing Hearts.
Kalyanasundaram A, Li N, Gardner ML, Artiga EJ, Hansen BJ, Webb A, Freitas MA, Pietrzak M, Whitson BA, Mokadam NA, Janssen PML, Mohler PJ, Fedorov VV. Kalyanasundaram A, et al. Among authors: mohler pj. Circulation. 2021 Jul 13;144(2):126-143. doi: 10.1161/CIRCULATIONAHA.120.051583. Epub 2021 Apr 20. Circulation. 2021. PMID: 33874740 Free PMC article.
Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation.
Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, Dobrev D, Wehrens XH, Mohler PJ. Cunha SR, et al. Among authors: mohler pj. Circulation. 2011 Sep 13;124(11):1212-22. doi: 10.1161/CIRCULATIONAHA.111.023986. Epub 2011 Aug 22. Circulation. 2011. PMID: 21859974 Free PMC article.
Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.
Koval OM, Snyder JS, Wolf RM, Pavlovicz RE, Glynn P, Curran J, Leymaster ND, Dun W, Wright PJ, Cardona N, Qian L, Mitchell CC, Boyden PA, Binkley PF, Li C, Anderson ME, Mohler PJ, Hund TJ. Koval OM, et al. Among authors: mohler pj. Circulation. 2012 Oct 23;126(17):2084-94. doi: 10.1161/CIRCULATIONAHA.112.105320. Epub 2012 Sep 24. Circulation. 2012. PMID: 23008441 Free PMC article.
Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.
Glukhov AV, Kalyanasundaram A, Lou Q, Hage LT, Hansen BJ, Belevych AE, Mohler PJ, Knollmann BC, Periasamy M, Györke S, Fedorov VV. Glukhov AV, et al. Among authors: mohler pj. Eur Heart J. 2015 Mar 14;36(11):686-97. doi: 10.1093/eurheartj/eht452. Epub 2013 Nov 11. Eur Heart J. 2015. PMID: 24216388 Free PMC article.
EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology.
Curran J, Makara MA, Little SC, Musa H, Liu B, Wu X, Polina I, Alecusan JS, Wright P, Li J, Billman GE, Boyden PA, Gyorke S, Band H, Hund TJ, Mohler PJ. Curran J, et al. Among authors: mohler pj. Circ Res. 2014 Jun 20;115(1):68-78. doi: 10.1161/CIRCRESAHA.115.304149. Epub 2014 Apr 23. Circ Res. 2014. PMID: 24759929 Free PMC article.
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Lou Q, Hansen BJ, Fedorenko O, Csepe TA, Kalyanasundaram A, Li N, Hage LT, Glukhov AV, Billman GE, Weiss R, Mohler PJ, Györke S, Biesiadecki BJ, Carnes CA, Fedorov VV. Lou Q, et al. Among authors: mohler pj. Circulation. 2014 Jul 22;130(4):315-24. doi: 10.1161/CIRCULATIONAHA.113.007086. Epub 2014 May 16. Circulation. 2014. PMID: 24838362 Free PMC article.
270 results