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Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia.
Aue G, Njuguna N, Tian X, Soto S, Hughes T, Vire B, Keyvanfar K, Gibellini F, Valdez J, Boss C, Samsel L, McCoy JP Jr, Wilson WH, Pittaluga S, Wiestner A. Aue G, et al. Among authors: keyvanfar k. Haematologica. 2009 Sep;94(9):1266-73. doi: 10.3324/haematol.2009.005835. Haematologica. 2009. PMID: 19734418 Free PMC article. Clinical Trial.
Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1.
Herishanu Y, Gibellini F, Njuguna N, Hazan-Halevy I, Farooqui M, Bern S, Keyvanfar K, Lee E, Wilson W, Wiestner A. Herishanu Y, et al. Among authors: keyvanfar k. Leuk Lymphoma. 2011 Sep;52(9):1758-69. doi: 10.3109/10428194.2011.569962. Epub 2011 Jun 8. Leuk Lymphoma. 2011. PMID: 21649540 Free PMC article.
Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy.
Herman SE, Sun X, McAuley EM, Hsieh MM, Pittaluga S, Raffeld M, Liu D, Keyvanfar K, Chapman CM, Chen J, Buggy JJ, Aue G, Tisdale JF, Pérez-Galán P, Wiestner A. Herman SE, et al. Among authors: keyvanfar k. Leukemia. 2013 Dec;27(12):2311-21. doi: 10.1038/leu.2013.131. Epub 2013 Apr 26. Leukemia. 2013. PMID: 23619564 Free PMC article.
Potentiating CD20 monoclonal antibody therapy by targeting complement C3 fragment covalently deposited on lymphoma cells.
Baskar S, Peng H, Gaglione EM, Carstens EJ, Lindorfer MA, Ahn IE, Herman SEM, Skarzynski M, Chang J, Keyvanfar K, Butera V, Blackburn AZ, Vire B, Maric I, Stetler-Stevenson M, Yuan CM, Eckhaus MA, Soto S, Farooqui MZH, Taylor RP, Rader C, Wiestner A. Baskar S, et al. Among authors: keyvanfar k. Blood. 2025 Jan 7:blood.2024024846. doi: 10.1182/blood.2024024846. Online ahead of print. Blood. 2025. PMID: 39774793
Clonal dominance of chronic myelogenous leukemia is associated with diminished sensitivity to the antiproliferative effects of neutrophil elastase.
El-Ouriaghli F, Sloand E, Mainwaring L, Fujiwara H, Keyvanfar K, Melenhorst JJ, Rezvani K, Sconocchia G, Solomon S, Hensel N, Barrett AJ. El-Ouriaghli F, et al. Among authors: keyvanfar k. Blood. 2003 Nov 15;102(10):3786-92. doi: 10.1182/blood-2003-03-0861. Epub 2003 Jul 31. Blood. 2003. PMID: 12893759 Free article.
82 results