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Rabbit antithymocyte globulin (thymoglobulin) impairs the thymic output of both conventional and regulatory CD4+ T cells after allogeneic hematopoietic stem cell transplantation in adult patients.
Na IK, Wittenbecher F, Dziubianau M, Herholz A, Mensen A, Kunkel D, Blau O, Blau I, Thiel E, Uharek L, Scheibenbogen C, Rieger K, Thiel A. Na IK, et al. Among authors: thiel e, thiel a. Haematologica. 2013 Jan;98(1):23-30. doi: 10.3324/haematol.2012.067611. Epub 2012 Jul 16. Haematologica. 2013. PMID: 22801968 Free PMC article.
A converse 4-1BB and CD40 ligand expression pattern delineates activated regulatory T cells (Treg) and conventional T cells enabling direct isolation of alloantigen-reactive natural Foxp3+ Treg.
Schoenbrunn A, Frentsch M, Kohler S, Keye J, Dooms H, Moewes B, Dong J, Loddenkemper C, Sieper J, Wu P, Romagnani C, Matzmohr N, Thiel A. Schoenbrunn A, et al. Among authors: thiel a. J Immunol. 2012 Dec 15;189(12):5985-94. doi: 10.4049/jimmunol.1201090. Epub 2012 Nov 16. J Immunol. 2012. PMID: 23162126
CD40L expression permits CD8+ T cells to execute immunologic helper functions.
Frentsch M, Stark R, Matzmohr N, Meier S, Durlanik S, Schulz AR, Stervbo U, Jürchott K, Gebhardt F, Heine G, Reuter MA, Betts MR, Busch D, Thiel A. Frentsch M, et al. Among authors: thiel a. Blood. 2013 Jul 18;122(3):405-12. doi: 10.1182/blood-2013-02-483586. Epub 2013 May 29. Blood. 2013. PMID: 23719298 Free PMC article.
688 results