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Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension.
Daneva Z, Marziano C, Ottolini M, Chen YL, Baker TM, Kuppusamy M, Zhang A, Ta HQ, Reagan CE, Mihalek AD, Kasetti RB, Shen Y, Isakson BE, Minshall RD, Zode GS, Goncharova EA, Laubach VE, Sonkusare SK. Daneva Z, et al. Among authors: goncharova ea. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2023130118. doi: 10.1073/pnas.2023130118. Proc Natl Acad Sci U S A. 2021. PMID: 33879616 Free PMC article.
Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension.
Farkas D, Thompson AAR, Bhagwani AR, Hultman S, Ji H, Kotha N, Farr G, Arnold ND, Braithwaite A, Casbolt H, Cole JE, Sabroe I, Monaco C, Cool CD, Goncharova EA, Lawrie A, Farkas L. Farkas D, et al. Among authors: goncharova ea. Am J Respir Crit Care Med. 2019 Jan 15;199(2):199-210. doi: 10.1164/rccm.201707-1370OC. Am J Respir Crit Care Med. 2019. PMID: 30211629 Free PMC article.
Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension.
Kudryashova TV, Shen Y, Pena A, Cronin E, Okorie E, Goncharov DA, Goncharova EA. Kudryashova TV, et al. Among authors: goncharova ea. Int J Mol Sci. 2018 Sep 28;19(10):2957. doi: 10.3390/ijms19102957. Int J Mol Sci. 2018. PMID: 30274147 Free PMC article.
Frataxin deficiency promotes endothelial senescence in pulmonary hypertension.
Culley MK, Zhao J, Tai YY, Tang Y, Perk D, Negi V, Yu Q, Woodcock CC, Handen A, Speyer G, Kim S, Lai YC, Satoh T, Watson AM, Aaraj YA, Sembrat J, Rojas M, Goncharov D, Goncharova EA, Khan OF, Anderson DG, Dahlman JE, Gurkar AU, Lafyatis R, Fayyaz AU, Redfield MM, Gladwin MT, Rabinovitch M, Gu M, Bertero T, Chan SY. Culley MK, et al. Among authors: goncharova ea. J Clin Invest. 2021 Jun 1;131(11):e136459. doi: 10.1172/JCI136459. J Clin Invest. 2021. PMID: 33905372 Free PMC article.
102 results