Sansom MSP - Search Results

1

Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation.

Hammond K, Cipcigan F, Al Nahas K, Losasso V, Lewis H, Cama J, Martelli F, Simcock PW, Fletcher M, Ravi J, Stansfeld PJ, Pagliara S, Hoogenboom BW, Keyser UF, Sansom MSP, Crain J, Ryadnov MG. Hammond K, et al. Among authors: sansom msp. ACS Nano. 2021 Jun 22;15(6):9679-9689. doi: 10.1021/acsnano.1c00218. Epub 2021 Apr 22. ACS Nano. 2021. PMID: 33885289 Free PMC article.

2

Molecular modeling and simulation studies of ion channel structures, dynamics and mechanisms.

Tai K, Fowler P, Mokrab Y, Stansfeld P, Sansom MS. Tai K, et al. Methods Cell Biol. 2008;90:233-65. doi: 10.1016/S0091-679X(08)00812-1. Methods Cell Biol. 2008. PMID: 19195554

3

Ion-blocking sites of the Kir2.1 channel revealed by multiscale modeling.

Tai K, Stansfeld PJ, Sansom MS. Tai K, et al. Biochemistry. 2009 Sep 15;48(36):8758-63. doi: 10.1021/bi9007808. Biochemistry. 2009. PMID: 19653656

4

Simulations of the BM2 proton channel transmembrane domain from influenza virus B.

Rouse SL, Carpenter T, Stansfeld PJ, Sansom MS. Rouse SL, et al. Biochemistry. 2009 Oct 27;48(42):9949-51. doi: 10.1021/bi901166n. Biochemistry. 2009. PMID: 19780586

5

PIP(2)-binding site in Kir channels: definition by multiscale biomolecular simulations.

Stansfeld PJ, Hopkinson R, Ashcroft FM, Sansom MS. Stansfeld PJ, et al. Biochemistry. 2009 Nov 24;48(46):10926-33. doi: 10.1021/bi9013193. Biochemistry. 2009. PMID: 19839652 Free PMC article.

6

Lipidbook: a public repository for force-field parameters used in membrane simulations.

Domański J, Stansfeld PJ, Sansom MS, Beckstein O. Domański J, et al. J Membr Biol. 2010 Aug;236(3):255-8. doi: 10.1007/s00232-010-9296-8. Epub 2010 Aug 11. J Membr Biol. 2010. PMID: 20700585

7

A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated.

Männikkö R, Stansfeld PJ, Ashcroft AS, Hattersley AT, Sansom MS, Ellard S, Ashcroft FM. Männikkö R, et al. J Physiol. 2011 Jul 1;589(Pt 13):3071-83. doi: 10.1113/jphysiol.2011.209700. Epub 2011 May 3. J Physiol. 2011. PMID: 21540348 Free PMC article.

8

Biophysical and computational studies of membrane penetration by the GRP1 pleckstrin homology domain.

Lumb CN, He J, Xue Y, Stansfeld PJ, Stahelin RV, Kutateladze TG, Sansom MS. Lumb CN, et al. Structure. 2011 Sep 7;19(9):1338-46. doi: 10.1016/j.str.2011.04.010. Structure. 2011. PMID: 21893292 Free PMC article.

9

Molecular simulation approaches to membrane proteins.

Stansfeld PJ, Sansom MS. Stansfeld PJ, et al. Structure. 2011 Nov 9;19(11):1562-72. doi: 10.1016/j.str.2011.10.002. Structure. 2011. PMID: 22078556 Free article. Review.

10

Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.

Schmidt MR, Stansfeld PJ, Tucker SJ, Sansom MS. Schmidt MR, et al. Biochemistry. 2013 Jan 15;52(2):279-81. doi: 10.1021/bi301350s. Epub 2012 Dec 28. Biochemistry. 2013. PMID: 23270460 Free PMC article.

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