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ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance.
Jang SC, Economides KD, Moniz RJ, Sia CL, Lewis N, McCoy C, Zi T, Zhang K, Harrison RA, Lim J, Dey J, Grenley M, Kirwin K, Ross NL, Bourdeau R, Villiger-Oberbek A, Estes S, Xu K, Sanchez-Salazar J, Dooley K, Dahlberg WK, Williams DE, Sathyanarayanan S. Jang SC, et al. Among authors: zi t. Commun Biol. 2021 Apr 22;4(1):497. doi: 10.1038/s42003-021-02004-5. Commun Biol. 2021. PMID: 33888863 Free PMC article.
Exosome Surface Display of IL12 Results in Tumor-Retained Pharmacology with Superior Potency and Limited Systemic Exposure Compared with Recombinant IL12.
Lewis ND, Sia CL, Kirwin K, Haupt S, Mahimkar G, Zi T, Xu K, Dooley K, Jang SC, Choi B, Boutin A, Grube A, McCoy C, Sanchez-Salazar J, Doherty M, Gaidukov L, Estes S, Economides KD, Williams DE, Sathyanarayanan S. Lewis ND, et al. Among authors: zi t. Mol Cancer Ther. 2021 Mar;20(3):523-534. doi: 10.1158/1535-7163.MCT-20-0484. Epub 2020 Dec 21. Mol Cancer Ther. 2021. PMID: 33443094
Exosome-mediated genetic reprogramming of tumor-associated macrophages by exoASO-STAT6 leads to potent monotherapy antitumor activity.
Kamerkar S, Leng C, Burenkova O, Jang SC, McCoy C, Zhang K, Dooley K, Kasera S, Zi T, Sisó S, Dahlberg W, Sia CL, Patel S, Schmidt K, Economides K, Soos T, Burzyn D, Sathyanarayanan S. Kamerkar S, et al. Among authors: zi t. Sci Adv. 2022 Feb 18;8(7):eabj7002. doi: 10.1126/sciadv.abj7002. Epub 2022 Feb 18. Sci Adv. 2022. PMID: 35179953 Free PMC article.
In Vitro Evaluation of [3H]CPPC as a Tool Radioligand for CSF-1R.
Knight AC, Varlow C, Zi T, Liang SH, Josephson L, Schmidt K, Patel S, Vasdev N. Knight AC, et al. Among authors: zi t. ACS Chem Neurosci. 2021 Mar 17;12(6):998-1006. doi: 10.1021/acschemneuro.0c00802. Epub 2021 Mar 5. ACS Chem Neurosci. 2021. PMID: 33667059 Free PMC article.
Spontaneous genomic alterations in a chimeric model of colorectal cancer enable metastasis and guide effective combinatorial therapy.
Zhou Y, Rideout WM 3rd, Bressel A, Yalavarthi S, Zi T, Potz D, Farlow S, Brodeur J, Monti A, Reddipalli S, Xiao Q, Bottega S, Feng B, Chiu MI, Bosenberg M, Heyer J. Zhou Y, et al. Among authors: zi t. PLoS One. 2014 Aug 27;9(8):e105886. doi: 10.1371/journal.pone.0105886. eCollection 2014. PLoS One. 2014. PMID: 25162504 Free PMC article.
48 results