Knauf JA - Search Results

1

Co-inhibition of SMAD and MAPK signaling enhances 124I uptake in BRAF-mutant thyroid cancers.

Luckett KA, Cracchiolo JR, Krishnamoorthy GP, Leandro-Garcia LJ, Nagarajah J, Saqcena M, Lester R, Im SY, Zhao Z, Lowe SW, de Stanchina E, Sherman EJ, Ho AL, Leach SD, Knauf JA, Fagin JA. Luckett KA, et al. Among authors: knauf ja. Endocr Relat Cancer. 2021 May 18;28(6):391-402. doi: 10.1530/ERC-21-0017. Endocr Relat Cancer. 2021. PMID: 33890869 Free PMC article.

2

The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.

Saavedra HI, Knauf JA, Shirokawa JM, Wang J, Ouyang B, Elisei R, Stambrook PJ, Fagin JA. Saavedra HI, et al. Among authors: knauf ja. Oncogene. 2000 Aug 10;19(34):3948-54. doi: 10.1038/sj.onc.1203723. Oncogene. 2000. PMID: 10951588

3

Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon.

Knauf JA, Ward LS, Nikiforov YE, Nikiforova M, Puxeddu E, Medvedovic M, Liron T, Mochly-Rosen D, Fagin JA. Knauf JA, et al. J Clin Endocrinol Metab. 2002 May;87(5):2150-9. doi: 10.1210/jcem.87.5.8441. J Clin Endocrinol Metab. 2002. PMID: 11994357

4

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.

Kimura ET, Nikiforova MN, Zhu Z, Knauf JA, Nikiforov YE, Fagin JA. Kimura ET, et al. Among authors: knauf ja. Cancer Res. 2003 Apr 1;63(7):1454-7. Cancer Res. 2003. PMID: 12670889

5

Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels.

Wang J, Knauf JA, Basu S, Puxeddu E, Kuroda H, Santoro M, Fusco A, Fagin JA. Wang J, et al. Among authors: knauf ja. Mol Endocrinol. 2003 Jul;17(7):1425-36. doi: 10.1210/me.2003-0041. Epub 2003 Apr 10. Mol Endocrinol. 2003. PMID: 12690093

6

RET/PTC-induced dedifferentiation of thyroid cells is mediated through Y1062 signaling through SHC-RAS-MAP kinase.

Knauf JA, Kuroda H, Basu S, Fagin JA. Knauf JA, et al. Oncogene. 2003 Jul 10;22(28):4406-12. doi: 10.1038/sj.onc.1206602. Oncogene. 2003. PMID: 12853977

7

Acute expression of RET/PTC induces isozyme-specific activation and subsequent downregulation of PKCepsilon in PCCL3 thyroid cells.

Knauf JA, Ouyang B, Croyle M, Kimura E, Fagin JA. Knauf JA, et al. Oncogene. 2003 Oct 9;22(44):6830-8. doi: 10.1038/sj.onc.1206829. Oncogene. 2003. PMID: 14534528

8

Microsomal prostaglandin E2 synthase-1 is induced by conditional expression of RET/PTC in thyroid PCCL3 cells through the activation of the MEK-ERK pathway.

Puxeddu E, Mitsutake N, Knauf JA, Moretti S, Kim HW, Seta KA, Brockman D, Myatt L, Millhorn DE, Fagin JA. Puxeddu E, et al. Among authors: knauf ja. J Biol Chem. 2003 Dec 26;278(52):52131-8. doi: 10.1074/jbc.M306003200. Epub 2003 Oct 10. J Biol Chem. 2003. PMID: 14555660 Free article.

9

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas.

Nikiforova MN, Kimura ET, Gandhi M, Biddinger PW, Knauf JA, Basolo F, Zhu Z, Giannini R, Salvatore G, Fusco A, Santoro M, Fagin JA, Nikiforov YE. Nikiforova MN, et al. Among authors: knauf ja. J Clin Endocrinol Metab. 2003 Nov;88(11):5399-404. doi: 10.1210/jc.2003-030838. J Clin Endocrinol Metab. 2003. PMID: 14602780

10

Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas.

Nikiforova MN, Ciampi R, Salvatore G, Santoro M, Gandhi M, Knauf JA, Thomas GA, Jeremiah S, Bogdanova TI, Tronko MD, Fagin JA, Nikiforov YE. Nikiforova MN, et al. Among authors: knauf ja. Cancer Lett. 2004 Jun 8;209(1):1-6. doi: 10.1016/j.canlet.2003.12.004. Cancer Lett. 2004. PMID: 15145515

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