Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

27,889 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2.
Du G, Jiang J, Wu Q, Henning NJ, Donovan KA, Yue H, Che J, Lu W, Fischer ES, Bardeesy N, Zhang T, Gray NS. Du G, et al. Among authors: jiang j. Angew Chem Int Ed Engl. 2021 Jul 12;60(29):15905-15911. doi: 10.1002/anie.202101328. Epub 2021 Jun 14. Angew Chem Int Ed Engl. 2021. PMID: 33915015 Free PMC article.
Development of CDK2 and CDK5 Dual Degrader TMX-2172.
Teng M, Jiang J, He Z, Kwiatkowski NP, Donovan KA, Mills CE, Victor C, Hatcher JM, Fischer ES, Sorger PK, Zhang T, Gray NS. Teng M, et al. Among authors: jiang j. Angew Chem Int Ed Engl. 2020 Aug 10;59(33):13865-13870. doi: 10.1002/anie.202004087. Epub 2020 Jun 3. Angew Chem Int Ed Engl. 2020. PMID: 32415712 Free PMC article.
Discovery and resistance mechanism of a selective CDK12 degrader.
Jiang B, Gao Y, Che J, Lu W, Kaltheuner IH, Dries R, Kalocsay M, Berberich MJ, Jiang J, You I, Kwiatkowski N, Riching KM, Daniels DL, Sorger PK, Geyer M, Zhang T, Gray NS. Jiang B, et al. Among authors: jiang j. Nat Chem Biol. 2021 Jun;17(6):675-683. doi: 10.1038/s41589-021-00765-y. Epub 2021 Mar 22. Nat Chem Biol. 2021. PMID: 33753926 Free PMC article.
Discovery of Covalent MKK4/7 Dual Inhibitor.
Jiang J, Jiang B, He Z, Ficarro SB, Che J, Marto JA, Gao Y, Zhang T, Gray NS. Jiang J, et al. Among authors: jiang b. Cell Chem Biol. 2020 Dec 17;27(12):1553-1560.e8. doi: 10.1016/j.chembiol.2020.08.014. Epub 2020 Sep 10. Cell Chem Biol. 2020. PMID: 32916088 Free article.
Exploring the target scope of KEAP1 E3 ligase-based PROTACs.
Du G, Jiang J, Henning NJ, Safaee N, Koide E, Nowak RP, Donovan KA, Yoon H, You I, Yue H, Eleuteri NA, He Z, Li Z, Huang HT, Che J, Nabet B, Zhang T, Fischer ES, Gray NS. Du G, et al. Among authors: jiang j. Cell Chem Biol. 2022 Oct 20;29(10):1470-1481.e31. doi: 10.1016/j.chembiol.2022.08.003. Epub 2022 Sep 6. Cell Chem Biol. 2022. PMID: 36070758 Free PMC article.
Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma.
Jiang B, Jiang J, Kaltheuner IH, Iniguez AB, Anand K, Ferguson FM, Ficarro SB, Seong BKA, Greifenberg AK, Dust S, Kwiatkowski NP, Marto JA, Stegmaier K, Zhang T, Geyer M, Gray NS. Jiang B, et al. Among authors: jiang j. Eur J Med Chem. 2021 Oct 5;221:113481. doi: 10.1016/j.ejmech.2021.113481. Epub 2021 Apr 20. Eur J Med Chem. 2021. PMID: 33945934
Selective Macrocyclic Inhibitors of DYRK1A/B.
Powell CE, Hatcher JM, Jiang J, Vatsan PS, Che J, Gray NS. Powell CE, et al. Among authors: jiang j. ACS Med Chem Lett. 2022 Mar 8;13(4):577-585. doi: 10.1021/acsmedchemlett.1c00630. eCollection 2022 Apr 14. ACS Med Chem Lett. 2022. PMID: 35450378 Free PMC article.
27,889 results
You have reached the last available page of results. Please see the User Guide for more information.