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Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction.
Ito M, Yurube T, Kakutani K, Maeno K, Takada T, Terashima Y, Kakiuchi Y, Takeoka Y, Miyazaki S, Kuroda R, Nishida K. Ito M, et al. Among authors: takada t. Osteoarthritis Cartilage. 2017 Dec;25(12):2134-2146. doi: 10.1016/j.joca.2017.08.019. Epub 2017 Sep 6. Osteoarthritis Cartilage. 2017. PMID: 28888905 Free article.
Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction.
Kakiuchi Y, Yurube T, Kakutani K, Takada T, Ito M, Takeoka Y, Kanda Y, Miyazaki S, Kuroda R, Nishida K. Kakiuchi Y, et al. Among authors: takada t. Osteoarthritis Cartilage. 2019 Jun;27(6):965-976. doi: 10.1016/j.joca.2019.01.009. Epub 2019 Feb 1. Osteoarthritis Cartilage. 2019. PMID: 30716534 Free article.
Involvement of autophagy in the maintenance of rat intervertebral disc homeostasis: an in-vitro and in-vivo RNA interference study of Atg5.
Tsujimoto R, Yurube T, Takeoka Y, Kanda Y, Miyazaki K, Ohnishi H, Kakiuchi Y, Miyazaki S, Zhang Z, Takada T, Kuroda R, Kakutani K. Tsujimoto R, et al. Among authors: takada t. Osteoarthritis Cartilage. 2022 Mar;30(3):481-493. doi: 10.1016/j.joca.2021.12.004. Epub 2021 Dec 24. Osteoarthritis Cartilage. 2022. PMID: 34958937 Free article.
Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells.
Miyazaki S, Kakutani K, Yurube T, Maeno K, Takada T, Zhang Z, Kurakawa T, Terashima Y, Ito M, Ueha T, Matsushita T, Kuroda R, Kurosaka M, Nishida K. Miyazaki S, et al. Among authors: takada t. Arthritis Res Ther. 2015 Sep 15;17(1):253. doi: 10.1186/s13075-015-0763-6. Arthritis Res Ther. 2015. PMID: 26373839 Free PMC article.
Expression of adiponectin receptors in human and rat intervertebral disc cells and changes in receptor expression during disc degeneration using a rat tail temporary static compression model.
Terashima Y, Kakutani K, Yurube T, Takada T, Maeno K, Hirata H, Miyazaki S, Ito M, Kakiuchi Y, Takeoka Y, Kuroda R, Nishida K. Terashima Y, et al. Among authors: takada t. J Orthop Surg Res. 2016 Nov 22;11(1):147. doi: 10.1186/s13018-016-0481-z. J Orthop Surg Res. 2016. PMID: 27876065 Free PMC article.
1,520 results