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In Situ LSPR Sensing of Secreted Insulin in Organ-on-Chip.
Ortega MA, Rodríguez-Comas J, Yavas O, Velasco-Mallorquí F, Balaguer-Trias J, Parra V, Novials A, Servitja JM, Quidant R, Ramón-Azcón J. Ortega MA, et al. Among authors: novials a. Biosensors (Basel). 2021 Apr 28;11(5):138. doi: 10.3390/bios11050138. Biosensors (Basel). 2021. PMID: 33924867 Free PMC article.
Amyloid-induced β-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment.
Montane J, de Pablo S, Castaño C, Rodríguez-Comas J, Cadavez L, Obach M, Visa M, Alcarraz-Vizán G, Sanchez-Martinez M, Nonell-Canals A, Parrizas M, Servitja JM, Novials A. Montane J, et al. Among authors: novials a. FASEB J. 2017 Dec;31(12):5296-5306. doi: 10.1096/fj.201700236R. Epub 2017 Aug 15. FASEB J. 2017. PMID: 28821639 Free PMC article.
Collectively, these results uncover a novel beneficial effect of PBA on glucose homeostasis by restoring beta-cell function and preventing amyloid formation in mice expressing hIAPP in beta cells, highlighting the therapeutic potential of PBA for the treatment of T2D.-Mont …
Collectively, these results uncover a novel beneficial effect of PBA on glucose homeostasis by restoring beta-cell function and preve …
Stress-Induced MicroRNA-708 Impairs β-Cell Function and Growth.
Rodríguez-Comas J, Moreno-Asso A, Moreno-Vedia J, Martín M, Castaño C, Marzà-Florensa A, Bofill-De Ros X, Mir-Coll J, Montané J, Fillat C, Gasa R, Novials A, Servitja JM. Rodríguez-Comas J, et al. Among authors: novials a. Diabetes. 2017 Dec;66(12):3029-3040. doi: 10.2337/db16-1569. Epub 2017 Oct 2. Diabetes. 2017. PMID: 28970284
BACE2 suppression in mice aggravates the adverse metabolic consequences of an obesogenic diet.
Díaz-Catalán D, Alcarraz-Vizán G, Castaño C, de Pablo S, Rodríguez-Comas J, Fernández-Pérez A, Vallejo M, Ramírez S, Claret M, Parrizas M, Novials A, Servitja JM. Díaz-Catalán D, et al. Among authors: novials a. Mol Metab. 2021 Nov;53:101251. doi: 10.1016/j.molmet.2021.101251. Epub 2021 May 17. Mol Metab. 2021. PMID: 34015524 Free PMC article.
Direct reprogramming of human fibroblasts into insulin-producing cells using transcription factors.
Fontcuberta-PiSunyer M, García-Alamán A, Prades È, Téllez N, Alves-Figueiredo H, Ramos-Rodríguez M, Enrich C, Fernandez-Ruiz R, Cervantes S, Clua L, Ramón-Azcón J, Broca C, Wojtusciszyn A, Montserrat N, Pasquali L, Novials A, Servitja JM, Vidal J, Gomis R, Gasa R. Fontcuberta-PiSunyer M, et al. Among authors: novials a. Commun Biol. 2023 Mar 24;6(1):256. doi: 10.1038/s42003-023-04627-2. Commun Biol. 2023. PMID: 36964318 Free PMC article.
Exosomes and diabetes.
Castaño C, Novials A, Párrizas M. Castaño C, et al. Among authors: novials a. Diabetes Metab Res Rev. 2019 Mar;35(3):e3107. doi: 10.1002/dmrr.3107. Epub 2019 Jan 7. Diabetes Metab Res Rev. 2019. PMID: 30513130 Review.
111 results