Romão L - Search Results

1

Nonsense-mediated RNA decay and its bipolar function in cancer.

Nogueira G, Fernandes R, García-Moreno JF, Romão L. Nogueira G, et al. Among authors: romao l. Mol Cancer. 2021 Apr 29;20(1):72. doi: 10.1186/s12943-021-01364-0. Mol Cancer. 2021. PMID: 33926465 Free PMC article. Review.

2

Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.

Inácio A, Silva AL, Pinto J, Ji X, Morgado A, Almeida F, Faustino P, Lavinha J, Liebhaber SA, Romão L. Inácio A, et al. Among authors: romao l. J Biol Chem. 2004 Jul 30;279(31):32170-80. doi: 10.1074/jbc.M405024200. Epub 2004 May 25. J Biol Chem. 2004. PMID: 15161914 Free article.

3

Human alpha2-globin nonsense-mediated mRNA decay induced by a novel alpha-thalassaemia frameshift mutation at codon 22.

Pereira FJ, do Céu Silva M, Picanço I, Seixas MT, Ferrão A, Faustino P, Romão L. Pereira FJ, et al. Among authors: romao l. Br J Haematol. 2006 Apr;133(1):98-102. doi: 10.1111/j.1365-2141.2006.05971.x. Br J Haematol. 2006. PMID: 16512835 Free article.

4

Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay.

Silva AL, Ribeiro P, Inácio A, Liebhaber SA, Romão L. Silva AL, et al. Among authors: romao l. RNA. 2008 Mar;14(3):563-76. doi: 10.1261/rna.815108. Epub 2008 Jan 29. RNA. 2008. PMID: 18230761 Free PMC article.

5

The mammalian nonsense-mediated mRNA decay pathway: to decay or not to decay! Which players make the decision?

Silva AL, Romão L. Silva AL, et al. Among authors: romao l. FEBS Lett. 2009 Feb 4;583(3):499-505. doi: 10.1016/j.febslet.2008.12.058. Epub 2009 Jan 20. FEBS Lett. 2009. PMID: 19162024 Free article. Review.

6

Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations.

Peixeiro I, Inácio Â, Barbosa C, Silva AL, Liebhaber SA, Romão L. Peixeiro I, et al. Among authors: romao l. Nucleic Acids Res. 2012 Feb;40(3):1160-73. doi: 10.1093/nar/gkr820. Epub 2011 Oct 11. Nucleic Acids Res. 2012. PMID: 21989405 Free PMC article.

7

Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels.

Martins R, Proença D, Silva B, Barbosa C, Silva AL, Faustino P, Romão L. Martins R, et al. Among authors: romao l. PLoS One. 2012;7(4):e35461. doi: 10.1371/journal.pone.0035461. Epub 2012 Apr 18. PLoS One. 2012. PMID: 22530027 Free PMC article.

8

Unspliced precursors of NMD-sensitive β-globin transcripts exhibit decreased steady-state levels in erythroid cells.

Morgado A, Almeida F, Teixeira A, Silva AL, Romão L. Morgado A, et al. Among authors: romao l. PLoS One. 2012;7(6):e38505. doi: 10.1371/journal.pone.0038505. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675570 Free PMC article.

9

Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity.

Pereira FJ, Teixeira A, Kong J, Barbosa C, Silva AL, Marques-Ramos A, Liebhaber SA, Romão L. Pereira FJ, et al. Among authors: romao l. Nucleic Acids Res. 2015 Jul 27;43(13):6528-44. doi: 10.1093/nar/gkv588. Epub 2015 Jun 11. Nucleic Acids Res. 2015. PMID: 26068473 Free PMC article.

10

More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer.

Lacerda R, Menezes J, Romão L. Lacerda R, et al. Among authors: romao l. Cell Mol Life Sci. 2017 May;74(9):1659-1680. doi: 10.1007/s00018-016-2428-2. Epub 2016 Dec 2. Cell Mol Life Sci. 2017. PMID: 27913822 Free PMC article. Review.

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