Blundell TL - Search Results

1

Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.

Evans JC, Murugesan D, Post JM, Mendes V, Wang Z, Nahiyaan N, Lynch SL, Thompson S, Green SR, Ray PC, Hess J, Spry C, Coyne AG, Abell C, Boshoff HIM, Wyatt PG, Rhee KY, Blundell TL, Barry CE 3rd, Mizrahi V. Evans JC, et al. Among authors: blundell tl. ACS Infect Dis. 2021 Jun 11;7(6):1666-1679. doi: 10.1021/acsinfecdis.0c00904. Epub 2021 May 3. ACS Infect Dis. 2021. PMID: 33939919 Free PMC article.

2

The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily.

von Delft F, Lewendon A, Dhanaraj V, Blundell TL, Abell C, Smith AG. von Delft F, et al. Among authors: blundell tl. Structure. 2001 May 9;9(5):439-50. doi: 10.1016/s0969-2126(01)00604-9. Structure. 2001. PMID: 11377204 Free article.

3

High-throughput crystallography for lead discovery in drug design.

Blundell TL, Jhoti H, Abell C. Blundell TL, et al. Nat Rev Drug Discov. 2002 Jan;1(1):45-54. doi: 10.1038/nrd706. Nat Rev Drug Discov. 2002. PMID: 12119609 Review.

4

Structural insights into the evolution of the pantothenate-biosynthesis pathway.

Lobley CM, Schmitzberger F, Kilkenny ML, Whitney H, Ottenhof HH, Chakauya E, Webb ME, Birch LM, Tuck KL, Abell C, Smith AG, Blundell TL. Lobley CM, et al. Among authors: blundell tl. Biochem Soc Trans. 2003 Jun;31(Pt 3):563-71. doi: 10.1042/bst0310563. Biochem Soc Trans. 2003. PMID: 12773157

5

Comparative analysis of the Escherichia coli ketopantoate hydroxymethyltransferase crystal structure confirms that it is a member of the (betaalpha)8 phosphoenolpyruvate/pyruvate superfamily.

Schmitzberger F, Smith AG, Abell C, Blundell TL. Schmitzberger F, et al. Among authors: blundell tl. J Bacteriol. 2003 Jul;185(14):4163-71. doi: 10.1128/JB.185.14.4163-4171.2003. J Bacteriol. 2003. PMID: 12837791 Free PMC article.

6

Structure of E. coli ketopantoate hydroxymethyl transferase complexed with ketopantoate and Mg2+, solved by locating 160 selenomethionine sites.

von Delft F, Inoue T, Saldanha SA, Ottenhof HH, Schmitzberger F, Birch LM, Dhanaraj V, Witty M, Smith AG, Blundell TL, Abell C. von Delft F, et al. Among authors: blundell tl. Structure. 2003 Aug;11(8):985-96. doi: 10.1016/s0969-2126(03)00158-8. Structure. 2003. PMID: 12906829 Free article.

7

Organisation of the pantothenate (vitamin B5) biosynthesis pathway in higher plants.

Ottenhof HH, Ashurst JL, Whitney HM, Saldanha SA, Schmitzberger F, Gweon HS, Blundell TL, Abell C, Smith AG. Ottenhof HH, et al. Among authors: blundell tl. Plant J. 2004 Jan;37(1):61-72. doi: 10.1046/j.1365-313x.2003.01940.x. Plant J. 2004. PMID: 14675432 Free article.

8

The crystal structure of Escherichia coli ketopantoate reductase with NADP+ bound.

Lobley CM, Ciulli A, Whitney HM, Williams G, Smith AG, Abell C, Blundell TL. Lobley CM, et al. Among authors: blundell tl. Biochemistry. 2005 Jun 28;44(25):8930-9. doi: 10.1021/bi0502036. Biochemistry. 2005. PMID: 15966718

9

Pantothenate biosynthesis in higher plants.

Coxon KM, Chakauya E, Ottenhof HH, Whitney HM, Blundell TL, Abell C, Smith AG. Coxon KM, et al. Among authors: blundell tl. Biochem Soc Trans. 2005 Aug;33(Pt 4):743-6. doi: 10.1042/BST0330743. Biochem Soc Trans. 2005. PMID: 16042590 Review.

10

Crystal structures of Yersinia enterocolitica salicylate synthase and its complex with the reaction products salicylate and pyruvate.

Kerbarh O, Chirgadze DY, Blundell TL, Abell C. Kerbarh O, et al. Among authors: blundell tl. J Mol Biol. 2006 Mar 24;357(2):524-34. doi: 10.1016/j.jmb.2005.12.078. Epub 2006 Jan 11. J Mol Biol. 2006. PMID: 16434053

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