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Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.
Evans JC, Murugesan D, Post JM, Mendes V, Wang Z, Nahiyaan N, Lynch SL, Thompson S, Green SR, Ray PC, Hess J, Spry C, Coyne AG, Abell C, Boshoff HIM, Wyatt PG, Rhee KY, Blundell TL, Barry CE 3rd, Mizrahi V. Evans JC, et al. Among authors: mizrahi v. ACS Infect Dis. 2021 Jun 11;7(6):1666-1679. doi: 10.1021/acsinfecdis.0c00904. Epub 2021 May 3. ACS Infect Dis. 2021. PMID: 33939919 Free PMC article.
Expression of Mycobacterium smegmatis pyrazinamidase in Mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides.
Boshoff HI, Mizrahi V. Boshoff HI, et al. Among authors: mizrahi v. J Bacteriol. 2000 Oct;182(19):5479-85. doi: 10.1128/JB.182.19.5479-5485.2000. J Bacteriol. 2000. PMID: 10986252 Free PMC article.
Integration of the pzaA gene encoding the major PZase/nicotinamidase from Mycobacterium smegmatis (H. I. M. Boshoff and V. Mizrahi, J. Bacteriol. 180:5809-5814, 1998) or the M. tuberculosis pncA gene into the pncA mutant complemented its PZase/nicotinamidase defect. …
Integration of the pzaA gene encoding the major PZase/nicotinamidase from Mycobacterium smegmatis (H. I. M. Boshoff and V. Mizrahi
176 results