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Page 1
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.
Si L, Bai H, Rodas M, Cao W, Oh CY, Jiang A, Moller R, Hoagland D, Oishi K, Horiuchi S, Uhl S, Blanco-Melo D, Albrecht RA, Liu WC, Jordan T, Nilsson-Payant BE, Golynker I, Frere J, Logue J, Haupt R, McGrath M, Weston S, Zhang T, Plebani R, Soong M, Nurani A, Kim SM, Zhu DY, Benam KH, Goyal G, Gilpin SE, Prantil-Baun R, Gygi SP, Powers RK, Carlson KE, Frieman M, tenOever BR, Ingber DE. Si L, et al. Among authors: goyal g. Nat Biomed Eng. 2021 Aug;5(8):815-829. doi: 10.1038/s41551-021-00718-9. Epub 2021 May 3. Nat Biomed Eng. 2021. PMID: 33941899 Free PMC article.
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip.
Bein A, Kim S, Goyal G, Cao W, Fadel C, Naziripour A, Sharma S, Swenor B, LoGrande N, Nurani A, Miao VN, Navia AW, Ziegler CGK, Montañes JO, Prabhala P, Kim MS, Prantil-Baun R, Rodas M, Jiang A, O'Sullivan L, Tillya G, Shalek AK, Ingber DE. Bein A, et al. Among authors: goyal g. Front Pharmacol. 2021 Oct 25;12:718484. doi: 10.3389/fphar.2021.718484. eCollection 2021. Front Pharmacol. 2021. PMID: 34759819 Free PMC article.
Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ-on-a-Chip.
Goyal G, Prabhala P, Mahajan G, Bausk B, Gilboa T, Xie L, Zhai Y, Lazarovits R, Mansour A, Kim MS, Patil A, Curran D, Long JM, Sharma S, Junaid A, Cohen L, Ferrante TC, Levy O, Prantil-Baun R, Walt DR, Ingber DE. Goyal G, et al. Adv Sci (Weinh). 2022 May;9(14):e2103241. doi: 10.1002/advs.202103241. Epub 2022 Mar 14. Adv Sci (Weinh). 2022. PMID: 35289122 Free PMC article.
Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients.
Sperry MM, Oskotsky T, MariÄ I, Kaushal S, Takeda T, Horvath V, Powers RK, Rodas M, Furlong B, Soong M, Prabhala P, Goyal G, Carlson KE, Wong RJ, Kosti I, Le BL, Logue J, Hammond H, Frieman M, Stevenson DK, Ingber DE, Sirota M, Novak R. Sperry MM, et al. Among authors: goyal g. medRxiv [Preprint]. 2022 Jul 22:2022.04.12.22273802. doi: 10.1101/2022.04.12.22273802. medRxiv. 2022. Update in: PLoS Comput Biol. 2023 May 5;19(5):e1011050. doi: 10.1371/journal.pcbi.1011050 PMID: 35441166 Free PMC article. Updated. Preprint.
Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction.
Bein A, Fadel CW, Swenor B, Cao W, Powers RK, Camacho DM, Naziripour A, Parsons A, LoGrande N, Sharma S, Kim S, Jalili-Firoozinezhad S, Grant J, Breault DT, Iqbal J, Ali A, Denson LA, Moore SR, Prantil-Baun R, Goyal G, Ingber DE. Bein A, et al. Among authors: goyal g. Nat Biomed Eng. 2022 Nov;6(11):1236-1247. doi: 10.1038/s41551-022-00899-x. Epub 2022 Jun 23. Nat Biomed Eng. 2022. PMID: 35739419 Free PMC article.
PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19.
Logue J, Chakraborty AR, Johnson R, Goyal G, Rodas M, Taylor LJ, Baracco L, McGrath ME, Haupt R, Furlong BA, Soong M, Prabhala P, Horvath V, Carlson KE, Weston S, Ingber DE, DePamphilis ML, Frieman MB. Logue J, et al. Among authors: goyal g. Commun Biol. 2022 Aug 12;5(1):808. doi: 10.1038/s42003-022-03766-2. Commun Biol. 2022. PMID: 35962188 Free PMC article.
Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip.
Mahajan G, Doherty E, To T, Sutherland A, Grant J, Junaid A, Gulati A, LoGrande N, Izadifar Z, Timilsina SS, Horváth V, Plebani R, France M, Hood-Pishchany I, Rakoff-Nahoum S, Kwon DS, Goyal G, Prantil-Baun R, Ravel J, Ingber DE. Mahajan G, et al. Among authors: goyal g. Microbiome. 2022 Nov 26;10(1):201. doi: 10.1186/s40168-022-01400-1. Microbiome. 2022. PMID: 36434666 Free PMC article.
324 results