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Glucagon-like peptide-1 (GLP-1) receptor activation dilates cerebral arterioles, increases cerebral blood flow, and mediates remote (pre)conditioning neuroprotection against ischaemic stroke.
Nizari S, Basalay M, Chapman P, Korte N, Korsak A, Christie IN, Theparambil SM, Davidson SM, Reimann F, Trapp S, Yellon DM, Gourine AV. Nizari S, et al. Basic Res Cardiol. 2021 May 3;116(1):32. doi: 10.1007/s00395-021-00873-9. Basic Res Cardiol. 2021. PMID: 33942194 Free PMC article.
CO2 signaling mediates neurovascular coupling in the cerebral cortex.
Hosford PS, Wells JA, Nizari S, Christie IN, Theparambil SM, Castro PA, Hadjihambi A, Barros LF, Ruminot I, Lythgoe MF, Gourine AV. Hosford PS, et al. Among authors: nizari s. Nat Commun. 2022 Apr 19;13(1):2125. doi: 10.1038/s41467-022-29622-9. Nat Commun. 2022. PMID: 35440557 Free PMC article.
Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia.
Christie IN, Theparambil SM, Braga A, Doronin M, Hosford PS, Brazhe A, Mascarenhas A, Nizari S, Hadjihambi A, Wells JA, Hobbs A, Semyanov A, Abramov AY, Angelova PR, Gourine AV. Christie IN, et al. Among authors: nizari s. Cell Rep. 2023 Dec 26;42(12):113514. doi: 10.1016/j.celrep.2023.113514. Epub 2023 Nov 30. Cell Rep. 2023. PMID: 38041814 Free PMC article.
Neuroprotection in glaucoma - Is there a future role?
Baltmr A, Duggan J, Nizari S, Salt TE, Cordeiro MF. Baltmr A, et al. Among authors: nizari s. Exp Eye Res. 2010 Nov;91(5):554-66. doi: 10.1016/j.exer.2010.08.009. Epub 2010 Aug 26. Exp Eye Res. 2010. PMID: 20800593 Review.
21 results