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Page 1
Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer.
Börcsök J, Sztupinszki Z, Bekele R, Gao SP, Diossy M, Samant AS, Dillon KM, Tisza V, Spisák S, Rusz O, Csabai I, Pappot H, Frazier ZJ, Konieczkowski DJ, Liu D, Vasani N, Rodrigues JA, Solit DB, Hoffman-Censits JH, Plimack ER, Rosenberg JE, Lazaro JB, Taplin ME, Iyer G, Brunak S, Lozsa R, Van Allen EM, Szüts D, Mouw KW, Szallasi Z. Börcsök J, et al. Clin Cancer Res. 2021 Apr 1;27(7):2011-2022. doi: 10.1158/1078-0432.CCR-20-3316. Epub 2020 Nov 18. Clin Cancer Res. 2021. PMID: 33208343 Free PMC article.
Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers.
Guo J, Zhou Y, Xu C, Chen Q, Sztupinszki Z, Börcsök J, Xu C, Ye F, Tang W, Kang J, Yang L, Zhong J, Zhong T, Hu T, Yu R, Szallasi Z, Deng X, Li Q. Guo J, et al. Among authors: borcsok j. Cancer Res. 2021 Aug 15;81(16):4205-4217. doi: 10.1158/0008-5472.CAN-21-0086. Epub 2021 Jul 2. Cancer Res. 2021. PMID: 34215622 Free PMC article.
RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics.
Bekele RT, Samant AS, Nassar AH, So J, Garcia EP, Curran CR, Hwang JH, Mayhew DL, Nag A, Thorner AR, Börcsök J, Sztupinszki Z, Pan CX, Bellmunt J, Kwiatkowski DJ, Sonpavde GP, Van Allen EM, Mouw KW. Bekele RT, et al. Among authors: borcsok j. J Clin Invest. 2021 Nov 15;131(22):e147849. doi: 10.1172/JCI147849. J Clin Invest. 2021. PMID: 34554931 Free PMC article.
Hierarchy and control of ageing-related methylation networks.
Palla G, Pollner P, Börcsök J, Major A, Molnár B, Csabai I. Palla G, et al. Among authors: borcsok j. PLoS Comput Biol. 2021 Sep 17;17(9):e1009327. doi: 10.1371/journal.pcbi.1009327. eCollection 2021 Sep. PLoS Comput Biol. 2021. PMID: 34534207 Free PMC article.
Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression.
Diossy M, Tisza V, Li H, Sahgal P, Zhou J, Sztupinszki Z, Young D, Nousome D, Kuo C, Jiang J, Chen Y, Ebner R, Sesterhenn IA, Moncur JT, Chesnut GT, Petrovics G, Klus GT, Valcz G, Nuzzo PV, Ribli D, Börcsök J, Prosz A, Krzystanek M, Ried T, Szuts D, Rizwan K, Kaochar S, Pathania S, D'Andrea AD, Csabai I, Srivastava S, Freedman ML, Dobi A, Spisak S, Szallasi Z. Diossy M, et al. Among authors: borcsok j. NPJ Precis Oncol. 2024 Sep 19;8(1):208. doi: 10.1038/s41698-024-00705-8. NPJ Precis Oncol. 2024. PMID: 39294262 Free PMC article.
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