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Page 1
Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor.
Löhn M, Plettenburg O, Ivashchenko Y, Kannt A, Hofmeister A, Kadereit D, Schaefer M, Linz W, Kohlmann M, Herbert JM, Janiak P, O'Connor SE, Ruetten H. Löhn M, et al. Among authors: plettenburg o, o connor se. Hypertension. 2009 Sep;54(3):676-83. doi: 10.1161/HYPERTENSIONAHA.109.134353. Epub 2009 Jul 13. Hypertension. 2009. PMID: 19597037
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC. Kyriakou E, et al. Among authors: plettenburg o. J Med Chem. 2018 Dec 27;61(24):11144-11157. doi: 10.1021/acs.jmedchem.8b01224. Epub 2018 Dec 7. J Med Chem. 2018. PMID: 30525586
Total Synthesis of GE81112A: An Orthoester-Based Approach.
Fayad S, Jafari A, Schuler SMM, Kurz M, Plettenburg O, Hammann PE, Bauer A, Jürjens G, Pöverlein C. Fayad S, et al. Among authors: plettenburg o. J Org Chem. 2023 May 5;88(9):5597-5608. doi: 10.1021/acs.joc.3c00094. Epub 2023 Apr 6. J Org Chem. 2023. PMID: 37023463 Free PMC article.
Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity.
Dawidowski M, Kalel VC, Napolitano V, Fino R, Schorpp K, Emmanouilidis L, Lenhart D, Ostertag M, Kaiser M, Kolonko M, Tippler B, Schliebs W, Dubin G, Mäser P, Tetko IV, Hadian K, Plettenburg O, Erdmann R, Sattler M, Popowicz GM. Dawidowski M, et al. Among authors: plettenburg o. J Med Chem. 2020 Jan 23;63(2):847-879. doi: 10.1021/acs.jmedchem.9b01876. Epub 2020 Jan 6. J Med Chem. 2020. PMID: 31860309
Structure-based design, synthesis and evaluation of a novel family of PEX5-PEX14 interaction inhibitors against Trypanosoma.
Napolitano V, Mróz P, Marciniak M, Kalel VC, Softley CA, Janna Olmos JD, Tippler BG, Schorpp K, Rioton S, Fröhlich T, Plettenburg O, Hadian K, Erdmann R, Sattler M, Popowicz GM, Dawidowski M, Dubin G. Napolitano V, et al. Among authors: plettenburg o. Eur J Med Chem. 2022 Dec 5;243:114778. doi: 10.1016/j.ejmech.2022.114778. Epub 2022 Sep 27. Eur J Med Chem. 2022. PMID: 36194937 Free article.
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.
Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K. Brenke JK, et al. Among authors: plettenburg o. J Biol Chem. 2018 Aug 24;293(34):13191-13203. doi: 10.1074/jbc.RA118.002649. Epub 2018 Jun 27. J Biol Chem. 2018. PMID: 29950522 Free PMC article.
63 results