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CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity.
Nguyen THO, Rowntree LC, Petersen J, Chua BY, Hensen L, Kedzierski L, van de Sandt CE, Chaurasia P, Tan HX, Habel JR, Zhang W, Allen LF, Earnest L, Mak KY, Juno JA, Wragg K, Mordant FL, Amanat F, Krammer F, Mifsud NA, Doolan DL, Flanagan KL, Sonda S, Kaur J, Wakim LM, Westall GP, James F, Mouhtouris E, Gordon CL, Holmes NE, Smibert OC, Trubiano JA, Cheng AC, Harcourt P, Clifton P, Crawford JC, Thomas PG, Wheatley AK, Kent SJ, Rossjohn J, Torresi J, Kedzierska K. Nguyen THO, et al. Among authors: juno ja. Immunity. 2021 May 11;54(5):1066-1082.e5. doi: 10.1016/j.immuni.2021.04.009. Epub 2021 Apr 15. Immunity. 2021. PMID: 33951417 Free PMC article.
Cytotoxic CD4 T Cells-Friend or Foe during Viral Infection?
Juno JA, van Bockel D, Kent SJ, Kelleher AD, Zaunders JJ, Munier CM. Juno JA, et al. Front Immunol. 2017 Jan 23;8:19. doi: 10.3389/fimmu.2017.00019. eCollection 2017. Front Immunol. 2017. PMID: 28167943 Free PMC article. Review.
101 results