O'Leary BR - Search Results

1

Epigenetic effects of pharmacologic ascorbate.

Steers GJ, Carroll RS, O'Leary BR, Cullen JJ. Steers GJ, et al. Among authors: o leary br. Oncotarget. 2021 Apr 27;12(9):876-877. doi: 10.18632/oncotarget.27911. eCollection 2021 Apr 27. Oncotarget. 2021. PMID: 33953841 Free PMC article. No abstract available.

2

Pharmacologic ascorbate (P-AscH^-) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma.

Wilkes JG, O'Leary BR, Du J, Klinger AR, Sibenaller ZA, Doskey CM, Gibson-Corley KN, Alexander MS, Tsai S, Buettner GR, Cullen JJ. Wilkes JG, et al. Clin Exp Metastasis. 2018 Feb;35(1-2):37-51. doi: 10.1007/s10585-018-9876-z. Epub 2018 Feb 2. Clin Exp Metastasis. 2018. PMID: 29396728 Free PMC article.

3

Pharmacological Ascorbate as an Adjuvant for Enhancing Radiation-Chemotherapy Responses in Gastric Adenocarcinoma.

O'Leary BR, Houwen FK, Johnson CL, Allen BG, Mezhir JJ, Berg DJ, Cullen JJ, Spitz DR. O'Leary BR, et al. Radiat Res. 2018 May;189(5):456-465. doi: 10.1667/RR14978.1. Epub 2018 Mar 16. Radiat Res. 2018. PMID: 29547353 Free PMC article.

4

Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer.

Alexander MS, Wilkes JG, Schroeder SR, Buettner GR, Wagner BA, Du J, Gibson-Corley K, O'Leary BR, Spitz DR, Buatti JM, Berg DJ, Bodeker KL, Vollstedt S, Brown HA, Allen BG, Cullen JJ. Alexander MS, et al. Cancer Res. 2018 Dec 15;78(24):6838-6851. doi: 10.1158/0008-5472.CAN-18-1680. Epub 2018 Sep 25. Cancer Res. 2018. PMID: 30254147 Free PMC article. Clinical Trial.

5

Enhanced Pharmacological Ascorbate Oxidation Radiosensitizes Pancreatic Cancer.

Alexander MS, O'Leary BR, Wilkes JG, Gibson AR, Wagner BA, Du J, Sarsour E, Hwang RF, Buettner GR, Cullen JJ. Alexander MS, et al. Radiat Res. 2019 Jan;191(1):43-51. doi: 10.1667/RR15189.1. Epub 2018 Oct 30. Radiat Res. 2019. PMID: 30376411 Free PMC article.

6

A model for the detection of pancreatic ductal adenocarcinoma circulating tumor cells.

Alexander MS, O'Leary BR, Moose D, Du J, Henry MD, Cullen JJ. Alexander MS, et al. J Biol Methods. 2018 Sep 5;5(3):e97. doi: 10.14440/jbm.2018.250. eCollection 2018. J Biol Methods. 2018. PMID: 31453247 Free PMC article.

7

Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity.

Gibson AR, O'Leary BR, Du J, Sarsour EH, Kalen AL, Wagner BA, Stolwijk JM, Falls-Hubert KC, Alexander MS, Carroll RS, Spitz DR, Buettner GR, Goswami PC, Cullen JJ. Gibson AR, et al. Cancer Res. 2020 Apr 1;80(7):1401-1413. doi: 10.1158/0008-5472.CAN-19-3094. Epub 2020 Feb 10. Cancer Res. 2020. PMID: 32041838 Free PMC article.

8

Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer.

Sarsour EH, Son JM, Kalen AL, Xiao W, Du J, Alexander MS, O'Leary BR, Cullen JJ, Goswami PC. Sarsour EH, et al. J Biol Chem. 2020 May 15;295(20):6946-6957. doi: 10.1074/jbc.RA120.012798. Epub 2020 Apr 7. J Biol Chem. 2020. PMID: 32265301 Free PMC article.

9

Pharmacological ascorbate inhibits pancreatic cancer metastases via a peroxide-mediated mechanism.

O'Leary BR, Alexander MS, Du J, Moose DL, Henry MD, Cullen JJ. O'Leary BR, et al. Sci Rep. 2020 Oct 19;10(1):17649. doi: 10.1038/s41598-020-74806-2. Sci Rep. 2020. PMID: 33077776 Free PMC article. Clinical Trial.

10

Catalase Modulates the Radio-Sensitization of Pancreatic Cancer Cells by Pharmacological Ascorbate.

Du J, Carroll RS, Steers GJ, Wagner BA, O'Leary BR, Jensen CS, Buettner GR, Cullen JJ. Du J, et al. Among authors: o leary br. Antioxidants (Basel). 2021 Apr 16;10(4):614. doi: 10.3390/antiox10040614. Antioxidants (Basel). 2021. PMID: 33923601 Free PMC article.

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