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An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes.
Sterjovski J, Roche M, Churchill MJ, Ellett A, Farrugia W, Gray LR, Cowley D, Poumbourios P, Lee B, Wesselingh SL, Cunningham AL, Ramsland PA, Gorry PR. Sterjovski J, et al. Among authors: poumbourios p. Virology. 2010 Sep 1;404(2):269-78. doi: 10.1016/j.virol.2010.05.006. Epub 2010 Jun 8. Virology. 2010. PMID: 20570309 Free PMC article.
Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 allele.
Gray L, Churchill MJ, Keane N, Sterjovski J, Ellett AM, Purcell DF, Poumbourios P, Kol C, Wang B, Saksena NK, Wesselingh SL, Price P, French M, Gabuzda D, Gorry PR. Gray L, et al. Among authors: poumbourios p. J Virol. 2006 Apr;80(7):3684-91. doi: 10.1128/JVI.80.7.3684-3691.2006. J Virol. 2006. PMID: 16537640 Free PMC article.
Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain.
Gray L, Roche M, Churchill MJ, Sterjovski J, Ellett A, Poumbourios P, Sherieff S, Wang B, Saksena N, Purcell DF, Wesselingh S, Cunningham AL, Brew BJ, Gabuzda D, Gorry PR. Gray L, et al. Among authors: poumbourios p. J Virol. 2009 Jun;83(11):5430-41. doi: 10.1128/JVI.02648-08. Epub 2009 Mar 25. J Virol. 2009. PMID: 19321618 Free PMC article.
Distinct functions for the membrane-proximal ectodomain region (MPER) of HIV-1 gp41 in cell-free and cell-cell viral transmission and cell-cell fusion.
Narasimhulu VGS, Bellamy-McIntyre AK, Laumaea AE, Lay CS, Harrison DN, King HAD, Drummer HE, Poumbourios P. Narasimhulu VGS, et al. Among authors: poumbourios p. J Biol Chem. 2018 Apr 20;293(16):6099-6120. doi: 10.1074/jbc.RA117.000537. Epub 2018 Mar 1. J Biol Chem. 2018. PMID: 29496992 Free PMC article.
59 results