Bzymek KP - Search Results

1

Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design.

Riley TP, Chou HT, Hu R, Bzymek KP, Correia AR, Partin AC, Li D, Gong D, Wang Z, Yu X, Manzanillo P, Garces F. Riley TP, et al. Among authors: bzymek kp. Front Immunol. 2021 Apr 22;12:660198. doi: 10.3389/fimmu.2021.660198. eCollection 2021. Front Immunol. 2021. PMID: 33968063 Free PMC article.

2

Rational selection of building blocks for the assembly of bispecific antibodies.

Gong D, Riley TP, Bzymek KP, Correia AR, Li D, Spahr C, Robinson JH, Case RB, Wang Z, Garces F. Gong D, et al. Among authors: bzymek kp. MAbs. 2021 Jan-Dec;13(1):1870058. doi: 10.1080/19420862.2020.1870058. MAbs. 2021. PMID: 33397191 Free PMC article.

3

Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.

Donaldson JM, Zer C, Avery KN, Bzymek KP, Horne DA, Williams JC. Donaldson JM, et al. Among authors: bzymek kp. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17456-61. doi: 10.1073/pnas.1307309110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101516 Free PMC article.

4

Development of a high affinity, non-covalent biologic to add functionality to Fabs.

Avery KN, Zer C, Bzymek KP, Williams JC. Avery KN, et al. Among authors: bzymek kp. Sci Rep. 2015 Jan 15;5:7817. doi: 10.1038/srep07817. Sci Rep. 2015. PMID: 25588710 Free PMC article.

5

Cyclization strategies of meditopes: affinity and diffraction studies of meditope-Fab complexes.

Bzymek KP, Ma Y, Avery KA, Horne DA, Williams JC. Bzymek KP, et al. Acta Crystallogr F Struct Biol Commun. 2016 Jun;72(Pt 6):434-42. doi: 10.1107/S2053230X16007202. Epub 2016 May 23. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27303895 Free PMC article.

6

Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.

Bzymek KP, Avery KA, Ma Y, Horne DA, Williams JC. Bzymek KP, et al. Acta Crystallogr F Struct Biol Commun. 2016 Nov 1;72(Pt 11):820-830. doi: 10.1107/S2053230X16016149. Epub 2016 Oct 24. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27834791 Free PMC article.

7

Engineering a high-affinity peptide binding site into the anti-CEA mAb M5A.

Zer C, Avery KN, Meyer K, Goodstein L, Bzymek KP, Singh G, Williams JC. Zer C, et al. Among authors: bzymek kp. Protein Eng Des Sel. 2017 Jun 1;30(6):409-417. doi: 10.1093/protein/gzx016. Protein Eng Des Sel. 2017. PMID: 28431161 Free PMC article.

8

Meditope-Fab interaction: threading the hole.

Bzymek KP, Ma Y, Avery KN, Horne DA, Williams JC. Bzymek KP, et al. Acta Crystallogr F Struct Biol Commun. 2017 Dec 1;73(Pt 12):688-694. doi: 10.1107/S2053230X17016272. Epub 2017 Nov 18. Acta Crystallogr F Struct Biol Commun. 2017. PMID: 29199990 Free PMC article.

9

Mechanically interlocked functionalization of monoclonal antibodies.

Bzymek KP, Puckett JW, Zer C, Xie J, Ma Y, King JD, Goodstein LH, Avery KN, Colcher D, Singh G, Horne DA, Williams JC. Bzymek KP, et al. Nat Commun. 2018 Apr 20;9(1):1580. doi: 10.1038/s41467-018-03976-5. Nat Commun. 2018. PMID: 29679060 Free PMC article.

10

Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.

King JD, Ma Y, Kuo YC, Bzymek KP, Goodstein LH, Meyer K, Moore RE, Crow D, Colcher DM, Singh G, Horne DA, Williams JC. King JD, et al. Among authors: bzymek kp. Bioconjug Chem. 2018 Jun 20;29(6):2074-2081. doi: 10.1021/acs.bioconjchem.8b00284. Epub 2018 May 25. Bioconjug Chem. 2018. PMID: 29763554 Free PMC article.

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