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AGO2 promotes tumor progression in KRAS-driven mouse models of non-small cell lung cancer.
Tien JC, Chugh S, Goodrum AE, Cheng Y, Mannan R, Zhang Y, Wang L, Dommeti VL, Wang X, Xu A, Hon J, Kenum C, Su F, Wang R, Cao X, Shankar S, Chinnaiyan AM. Tien JC, et al. Among authors: kenum c. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2026104118. doi: 10.1073/pnas.2026104118. Proc Natl Acad Sci U S A. 2021. PMID: 33972443 Free PMC article.
Biochemical characterization of the interaction between KRAS and Argonaute 2.
Waninger JJ, Beyett TS, Gadkari VV, Siebenaler RF, Kenum C, Shankar S, Ruotolo BT, Chinnaiyan AM, Tesmer JJG. Waninger JJ, et al. Among authors: kenum c. Biochem Biophys Rep. 2021 Dec 20;29:101191. doi: 10.1016/j.bbrep.2021.101191. eCollection 2022 Mar. Biochem Biophys Rep. 2021. PMID: 34988297 Free PMC article.
Argonaute 2 modulates EGFR-RAS signaling to promote mutant HRAS and NRAS-driven malignancies.
Siebenaler RF, Chugh S, Waninger JJ, Dommeti VL, Kenum C, Mody M, Gautam A, Patel N, Chu A, Bawa P, Hon J, Smith RD, Carlson H, Cao X, Tesmer JJG, Shankar S, Chinnaiyan AM. Siebenaler RF, et al. Among authors: kenum c. PNAS Nexus. 2022 Jul 28;1(3):pgac084. doi: 10.1093/pnasnexus/pgac084. eCollection 2022 Jul. PNAS Nexus. 2022. PMID: 35923912 Free PMC article.