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Combination of Crizotinib and Osimertinib in T790M+ EGFR-Mutant Non-Small Cell Lung Cancer with Emerging MET Amplification Post-Osimertinib Progression in a 10-Year Survivor: A Case Report.
Blasi M, Kazdal D, Thomas M, Christopoulos P, Kriegsmann M, Brandt R, Volckmar AL, Kirchner M, Heußel CP, Stenzinger A, Kuon J. Blasi M, et al. Among authors: brandt r. Case Rep Oncol. 2021 Mar 18;14(1):477-482. doi: 10.1159/000513904. eCollection 2021 Jan-Apr. Case Rep Oncol. 2021. PMID: 33976623 Free PMC article.
Histological and molecular plasticity of ALK-positive non-small-cell lung cancer under targeted therapy: a case report.
Ball M, Christopoulos P, Kirchner M, Allgäuer M, Brandt R, Winter H, Heußel CP, Herth F, Fröhling S, Savai R, Kriegsmann M, Schirmacher P, Peters S, Thomas M, Stenzinger A, Kazdal D. Ball M, et al. Among authors: brandt r. Cold Spring Harb Mol Case Stud. 2022 Apr 28;8(3):a006156. doi: 10.1101/mcs.a006156. Print 2022 Apr. Cold Spring Harb Mol Case Stud. 2022. PMID: 35058282 Free PMC article.
The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma.
Kirchner M, Kluck K, Brandt R, Volckmar AL, Penzel R, Kazdal D, Endris V, Neumann O, Seker-Cin H, Goldschmid H, Glade J, Allgäuer M, Kriegsmann M, Winter H, Muley T, Perner S, Frost N, Reck M, Fröhling S, Schirmacher P, Thomas M, Budczies J, Christopoulos P, Stenzinger A. Kirchner M, et al. Among authors: brandt r. ESMO Open. 2021 Oct;6(5):100253. doi: 10.1016/j.esmoop.2021.100253. Epub 2021 Sep 3. ESMO Open. 2021. PMID: 34487971 Free PMC article.
Synonymous EGFR variant p.Q787Q is neither prognostic nor predictive in patients with lung adenocarcinoma.
Leichsenring J, Volckmar AL, Magios N, Morais de Oliveira CM, Penzel R, Brandt R, Kirchner M, Bozorgmehr F, Thomas M, Schirmacher P, Warth A, Endris V, Stenzinger A. Leichsenring J, et al. Among authors: brandt r. Genes Chromosomes Cancer. 2017 Mar;56(3):214-220. doi: 10.1002/gcc.22427. Epub 2016 Nov 30. Genes Chromosomes Cancer. 2017. PMID: 27750395
Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases.
Volckmar AL, Leichsenring J, Kirchner M, Christopoulos P, Neumann O, Budczies J, Morais de Oliveira CM, Rempel E, Buchhalter I, Brandt R, Allgäuer M, Talla SB, von Winterfeld M, Herpel E, Goeppert B, Lier A, Winter H, Brummer T, Fröhling S, Faehling M, Fischer JR, Heußel CP, Herth F, Lasitschka F, Schirmacher P, Thomas M, Endris V, Penzel R, Stenzinger A. Volckmar AL, et al. Among authors: brandt r. Int J Cancer. 2019 Aug 1;145(3):649-661. doi: 10.1002/ijc.32133. Epub 2019 Feb 19. Int J Cancer. 2019. PMID: 30653256
Targeting rare and non-canonical driver variants in NSCLC - An uncharted clinical field.
Volckmar AL, Christopoulos P, Kirchner M, Allgäuer M, Neumann O, Budczies J, Rempel E, Horak P, Glade J, Goldschmid H, Seker-Cin H, Brandt R, Kriegsmann M, Leichsenring J, Winter H, Faehling M, Fischer JR, Heußel CP, Herth F, Brummer T, Fröhling S, Schirmacher P, Thomas M, Endris V, Penzel R, Kazdal D, Bochtler T, Stenzinger A. Volckmar AL, et al. Among authors: brandt r. Lung Cancer. 2021 Apr;154:131-141. doi: 10.1016/j.lungcan.2021.02.022. Epub 2021 Feb 19. Lung Cancer. 2021. PMID: 33667718
Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Pfarr N, Penzel R, Klauschen F, Heim D, Brandt R, Kazdal D, Jesinghaus M, Herpel E, Schirmacher P, Warth A, Weichert W, Endris V, Stenzinger A. Pfarr N, et al. Among authors: brandt r. Genes Chromosomes Cancer. 2016 Nov;55(11):821-33. doi: 10.1002/gcc.22378. Epub 2016 Jun 27. Genes Chromosomes Cancer. 2016. PMID: 27218826
Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts.
Kazdal D, Endris V, Allgäuer M, Kriegsmann M, Leichsenring J, Volckmar AL, Harms A, Kirchner M, Kriegsmann K, Neumann O, Brandt R, Talla SB, Rempel E, Ploeger C, von Winterfeld M, Christopoulos P, Merino DM, Stewart M, Allen J, Bischoff H, Meister M, Muley T, Herth F, Penzel R, Warth A, Winter H, Fröhling S, Peters S, Swanton C, Thomas M, Schirmacher P, Budczies J, Stenzinger A. Kazdal D, et al. Among authors: brandt r. J Thorac Oncol. 2019 Nov;14(11):1935-1947. doi: 10.1016/j.jtho.2019.07.006. Epub 2019 Jul 23. J Thorac Oncol. 2019. PMID: 31349062 Free article.
EGFR, KRAS, BRAF and ALK gene alterations in lung adenocarcinomas: patient outcome, interplay with morphology and immunophenotype.
Warth A, Penzel R, Lindenmaier H, Brandt R, Stenzinger A, Herpel E, Goeppert B, Thomas M, Herth FJ, Dienemann H, Schnabel PA, Schirmacher P, Hoffmann H, Muley T, Weichert W. Warth A, et al. Among authors: brandt r. Eur Respir J. 2014 Mar;43(3):872-83. doi: 10.1183/09031936.00018013. Epub 2013 Aug 29. Eur Respir J. 2014. PMID: 23988776 Free article.
KRAS/GNAS-testing by highly sensitive deep targeted next generation sequencing improves the endoscopic ultrasound-guided workup of suspected mucinous neoplasms of the pancreas.
Schmitz D, Kazdal D, Allgäuer M, Trunk M, Vornhusen S, Nahm AM, Doll M, Weingärtner S, Endris V, Penzel R, Kirchner M, Brandt R, Neumann O, Sültmann H, Budczies J, Kienle P, Magdeburg R, Hetjens S, Schirmacher P, Bergmann F, Rudi J, Stenzinger A, Volckmar AL. Schmitz D, et al. Among authors: brandt r. Genes Chromosomes Cancer. 2021 Jul;60(7):489-497. doi: 10.1002/gcc.22946. Epub 2021 Mar 16. Genes Chromosomes Cancer. 2021. PMID: 33686791
800 results