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The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.
Piao L, Fang YH, Cadete VJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL. Piao L, et al. Among authors: toth pt. J Mol Med (Berl). 2010 Jan;88(1):47-60. doi: 10.1007/s00109-009-0524-6. Epub 2009 Dec 1. J Mol Med (Berl). 2010. PMID: 19949938 Free PMC article.
Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
Archer SL, Marsboom G, Kim GH, Zhang HJ, Toth PT, Svensson EC, Dyck JR, Gomberg-Maitland M, Thébaud B, Husain AN, Cipriani N, Rehman J. Archer SL, et al. Among authors: toth pt. Circulation. 2010 Jun 22;121(24):2661-71. doi: 10.1161/CIRCULATIONAHA.109.916098. Epub 2010 Jun 7. Circulation. 2010. PMID: 20529999 Free PMC article.
A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion.
Thenappan T, Goel A, Marsboom G, Fang YH, Toth PT, Zhang HJ, Kajimoto H, Hong Z, Paul J, Wietholt C, Pogoriler J, Piao L, Rehman J, Archer SL. Thenappan T, et al. Among authors: toth pt. Am J Respir Crit Care Med. 2011 Apr 15;183(8):1080-91. doi: 10.1164/rccm.201008-1303OC. Epub 2010 Dec 10. Am J Respir Crit Care Med. 2011. PMID: 21148721 Free PMC article.
Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, Chen Y, Morrow E, Weir EK, Rehman J, Archer SL. Marsboom G, et al. Among authors: toth pt. Circ Res. 2012 May 25;110(11):1484-97. doi: 10.1161/CIRCRESAHA.111.263848. Epub 2012 Apr 17. Circ Res. 2012. PMID: 22511751 Free PMC article.
Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells.
Kohler EE, Wary KK, Li F, Chatterjee I, Urao N, Toth PT, Ushio-Fukai M, Rehman J, Park C, Malik AB. Kohler EE, et al. Among authors: toth pt. PLoS One. 2013 Dec 30;8(12):e85549. doi: 10.1371/journal.pone.0085549. eCollection 2013. PLoS One. 2013. PMID: 24386480 Free PMC article.
83 results