Krug RM - Search Results

1

Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture.

Bafna K, White K, Harish B, Rosales R, Ramelot TA, Acton TB, Moreno E, Kehrer T, Miorin L, Royer CA, García-Sastre A, Krug RM, Montelione GT. Bafna K, et al. Among authors: krug rm. Cell Rep. 2021 May 18;35(7):109133. doi: 10.1016/j.celrep.2021.109133. Epub 2021 Apr 27. Cell Rep. 2021. PMID: 33984267 Free PMC article.

2

An amino-terminal polypeptide fragment of the influenza virus NS1 protein possesses specific RNA-binding activity and largely helical backbone structure.

Qian XY, Chien CY, Lu Y, Montelione GT, Krug RM. Qian XY, et al. Among authors: krug rm. RNA. 1995 Nov;1(9):948-56. RNA. 1995. PMID: 8548659 Free PMC article.

3

RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids.

Wang W, Riedel K, Lynch P, Chien CY, Montelione GT, Krug RM. Wang W, et al. Among authors: krug rm. RNA. 1999 Feb;5(2):195-205. doi: 10.1017/s1355838299981621. RNA. 1999. PMID: 10024172 Free PMC article.

4

Efficient translation of mRNAs in influenza A virus-infected cells is independent of the viral 5' untranslated region.

Cassetti MC, Noah DL, Montelione GT, Krug RM. Cassetti MC, et al. Among authors: krug rm. Virology. 2001 Oct 25;289(2):180-5. doi: 10.1006/viro.2001.1149. Virology. 2001. PMID: 11689040 Free article.

5

Structural basis for ubiquitin-like ISG 15 protein binding to the NS1 protein of influenza B virus: a protein-protein interaction function that is not shared by the corresponding N-terminal domain of the NS1 protein of influenza A virus.

Yuan W, Aramini JM, Montelione GT, Krug RM. Yuan W, et al. Among authors: krug rm. Virology. 2002 Dec 20;304(2):291-301. doi: 10.1006/viro.2002.1663. Virology. 2002. PMID: 12504570 Free article.

6

Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode.

Chien CY, Xu Y, Xiao R, Aramini JM, Sahasrabudhe PV, Krug RM, Montelione GT. Chien CY, et al. Among authors: krug rm. Biochemistry. 2004 Feb 24;43(7):1950-62. doi: 10.1021/bi030176o. Biochemistry. 2004. PMID: 14967035

7

Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses.

Yin C, Khan JA, Swapna GV, Ertekin A, Krug RM, Tong L, Montelione GT. Yin C, et al. Among authors: krug rm. J Biol Chem. 2007 Jul 13;282(28):20584-92. doi: 10.1074/jbc.M611619200. Epub 2007 May 1. J Biol Chem. 2007. PMID: 17475623 Free article.

8

Structure of the iSH2 domain of human phosphatidylinositol 3-kinase p85β subunit reveals conformational plasticity in the interhelical turn region.

Schauder C, Ma LC, Krug RM, Montelione GT, Guan R. Schauder C, et al. Among authors: krug rm. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1;66(Pt 12):1567-71. doi: 10.1107/S1744309110041333. Epub 2010 Nov 16. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 21139197 Free PMC article.

9

Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors.

You L, Cho EJ, Leavitt J, Ma LC, Montelione GT, Anslyn EV, Krug RM, Ellington A, Robertus JD. You L, et al. Among authors: krug rm. Bioorg Med Chem Lett. 2011 May 15;21(10):3007-11. doi: 10.1016/j.bmcl.2011.03.042. Epub 2011 Mar 17. Bioorg Med Chem Lett. 2011. PMID: 21478016 Free PMC article.

10

Backbone and Ile-δ1, Leu, Val methyl 1H, 13C and 15N NMR chemical shift assignments for human interferon-stimulated gene 15 protein.

Yin C, Aramini JM, Ma LC, Cort JR, Swapna GV, Krug RM, Montelione GT. Yin C, et al. Among authors: krug rm. Biomol NMR Assign. 2011 Oct;5(2):215-9. doi: 10.1007/s12104-011-9303-8. Epub 2011 May 5. Biomol NMR Assign. 2011. PMID: 21544738 Free PMC article.

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