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Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecular heterogeneity, including non-recurring gene fusions characteristic of uterine and soft tissue sarcoma subtypes.
Acosta AM, Sholl LM, Dickson BC, McKenney JK, Gordetsky JB, Pins MR, Marino-Enriquez A, Dong F, Dubuc AM, Cin PD, Fletcher CDM. Acosta AM, et al. Mod Pathol. 2021 Sep;34(9):1763-1779. doi: 10.1038/s41379-021-00818-6. Epub 2021 May 13. Mod Pathol. 2021. PMID: 33986460 Free article.
Aberrant AKT activation drives well-differentiated liposarcoma.
Gutierrez A, Snyder EL, Marino-Enriquez A, Zhang YX, Sioletic S, Kozakewich E, Grebliunaite R, Ou WB, Sicinska E, Raut CP, Demetri GD, Perez-Atayde AR, Wagner AJ, Fletcher JA, Fletcher CD, Look AT. Gutierrez A, et al. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16386-91. doi: 10.1073/pnas.1106127108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2011. PMID: 21930930 Free PMC article.
Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes.
Jin Y, Möller E, Nord KH, Mandahl N, Von Steyern FV, Domanski HA, Mariño-Enríquez A, Magnusson L, Nilsson J, Sciot R, Fletcher CD, Debiec-Rychter M, Mertens F. Jin Y, et al. Genes Chromosomes Cancer. 2012 May;51(5):510-20. doi: 10.1002/gcc.21939. Epub 2012 Feb 15. Genes Chromosomes Cancer. 2012. PMID: 22337624 Free article.
94 results