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Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
Lin Y, Grinter SZ, Lu Z, Xu X, Wang HZ, Liang H, Hou P, Gao J, Clausen C, Shi J, Zhao W, Ma Z, Liu Y, White KM, Zhao L, Kang PW, Zhang G, Cohen IS, Zou X, Cui J. Lin Y, et al. Among authors: zhang g. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2024215118. doi: 10.1073/pnas.2024215118. Proc Natl Acad Sci U S A. 2021. PMID: 33990467 Free PMC article.
Ion sensing in the RCK1 domain of BK channels.
Zhang G, Huang SY, Yang J, Shi J, Yang X, Moller A, Zou X, Cui J. Zhang G, et al. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18700-5. doi: 10.1073/pnas.1010124107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937866 Free PMC article.
BK channels: multiple sensors, one activation gate.
Yang H, Zhang G, Cui J. Yang H, et al. Among authors: zhang g. Front Physiol. 2015 Feb 6;6:29. doi: 10.3389/fphys.2015.00029. eCollection 2015. Front Physiol. 2015. PMID: 25705194 Free PMC article. Review.
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