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Administration in fed state but not controlled release in the colon increases oral bioavailability of DF030263, a promising drug candidate for chronic lymphocytic leukemia.
Lee JB, Zang X, Zgair A, Ooi TQ, Foley DW, Voronin G, Kagan L, Soukarieh F, Gao R, Shao H, Soh WT, Kim TH, Kim MG, Yun HY, Wilson AJ, Fischer PM, Gershkovich P. Lee JB, et al. Among authors: wilson aj. Eur J Pharm Biopharm. 2021 Aug;165:106-112. doi: 10.1016/j.ejpb.2021.05.006. Epub 2021 May 12. Eur J Pharm Biopharm. 2021. PMID: 33991611
Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo.
Boehm J, Davis R, Murar CE, Li T, McCleland B, Dong S, Yan H, Kerns J, Moody CJ, Wilson AJ, Graves AP, Mentzer M, Qi H, Yonchuk J, Kou JP, Foley J, Sanchez Y, Podolin PL, Bolognese B, Booth-Genthe C, Galop M, Wolfe L, Carr R, Callahan JF. Boehm J, et al. Among authors: wilson aj. Bioorg Med Chem. 2019 Feb 15;27(4):579-588. doi: 10.1016/j.bmc.2018.12.026. Epub 2018 Dec 21. Bioorg Med Chem. 2019. PMID: 30626555
Keap calm, and carry on covalently.
Wilson AJ, Kerns JK, Callahan JF, Moody CJ. Wilson AJ, et al. J Med Chem. 2013 Oct 10;56(19):7463-76. doi: 10.1021/jm400224q. Epub 2013 Jul 25. J Med Chem. 2013. PMID: 23837912
Patient Experiences of Using Wearable Health Monitors During Cancer Treatment: A Qualitative Study.
Collinson S, Ingram-Walpole S, Jackson C, Soliman A, Chan AKC, Tholouli E, Balata H, Merchant M, Kirkby KJ, Sweeney S, Blackhall F, Bashall T, Searle E, Pan S, Braun M, Kitchen GB, Moore JA, Merchant Z, Wilson AJ. Collinson S, et al. Among authors: wilson aj. Clin Oncol (R Coll Radiol). 2025 Jan;37:103664. doi: 10.1016/j.clon.2024.10.036. Epub 2024 Oct 20. Clin Oncol (R Coll Radiol). 2025. PMID: 39550935
Selective breeding enhances coral heat tolerance to marine heatwaves.
Humanes A, Lachs L, Beauchamp E, Bukurou L, Buzzoni D, Bythell J, Craggs JRK, de la Torre Cerro R, Edwards AJ, Golbuu Y, Martinez HM, Palmowski P, van der Steeg E, Sweet M, Ward A, Wilson AJ, Guest JR. Humanes A, et al. Among authors: wilson aj. Nat Commun. 2024 Oct 14;15(1):8703. doi: 10.1038/s41467-024-52895-1. Nat Commun. 2024. PMID: 39402025 Free PMC article.
848 results